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Merck
CN

361615

Sigma-Aldrich

巴马汀氯化物 水合物

97%

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别名:
5,6-Dihydro-2,3,9,10-tetramethoxydibenzo[a,g]quinolizinium chloride hydrate (1:1:1)
经验公式(希尔记法):
C21H22ClNO4 · xH2O
分子量:
387.86 (anhydrous basis)
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

97%

杂质

~1.5 mol/mol methanol

mp

206-207 °C (dec.) (lit.)

SMILES字符串

[Cl-].[H]O[H].COc1cc2CC[n+]3cc4c(OC)c(OC)ccc4cc3-c2cc1OC

InChI

1S/C21H22NO4.ClH.H2O/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4;;/h5-6,9-12H,7-8H2,1-4H3;1H;1H2/q+1;;/p-1

InChI key

PIQNSCSNSSZUIT-UHFFFAOYSA-M

一般描述

Palmatine chloride hydrate (Palmatine) is an alkaloid. It is a potential phototoxin, and exhibits low quantum yields for fluorescence. Normal Raman spectra and DFT calculations of palmatine chloride hydrate is reported.

应用

Palmatine chloride hydrate (Palmatine) is suitable for use:
  • as alkaloid standard in the method validation for determination of berberine, hydrastine and canadine in goldenseal (Hydrastis canadensis L.) root powder
  • in the preparation of 8-heteroaryl-7,8-dihydroprotoberberine
  • in a study to investigate the FT-Raman and surface-enhanced Raman scattering (SERS) spectra of three related alkaloid dyes, namely palmatine, jatrorrhizine and coptisine

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 3

闪点(°F)

235.4 °F

闪点(°C)

113 °C

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Holly A Weber et al.
Journal of AOAC International, 86(3), 476-483 (2003-07-11)
A fast, practical ambient extraction methodology followed by isocratic liquid chromatography (LC) analysis with UV detection was validated for the determination of berberine, hydrastine, and canadine in goldenseal (Hydrastis canadensis L.) root powder. The method was also validated for palmatine
Sayaka Shinji et al.
Bioscience, biotechnology, and biochemistry, 84(1), 63-75 (2019-08-30)
A natural isoquinoline alkaloid, berberine, has been known to exhibit anti-tumor activity in various cancer cells via inducing cell cycle arrest. However, it has not been investigated whether berberine and its analogs inhibit the growth of rhabdomyosarcoma (RMS), which is
Surface-enhanced Raman scattering of protoberberine alkaloids.
Canamares MV, et al.
Journal of Raman Spectroscopy, 39(12), 1907-1914 (2008)
Fluorescence enhancement for alkaloids by anions: Spectroscopic and electrochemical characterizations.
Chung Y-L, et al.
Journal of Electroanalytical Chemistry, 610(1), 85-89 (2007)
Lenka Grycová et al.
Magnetic resonance in chemistry : MRC, 46(12), 1127-1134 (2008-09-11)
Adducts of the quaternary protoberberine alkaloids (QPA) berberine, palmatine, and coptisine were prepared with nucleophiles derived from pyrrole, pyrazole, imidazole, and 1,2,4-triazole. The products, 8-substituted 7,8-dihydroprotoberberines, were identified by mass spectrometry and 1D and 2D NMR spectroscopy, including (1)H--(15)N shift

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