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Merck
CN
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安全信息

361275

Sigma-Aldrich

3′-脱氧-3′-氟胸苷

97%

别名:

3′-Fluoro-2′,3′-dideoxythymidine, 3′-Fluorodeoxythymidine

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About This Item

经验公式（希尔记法）:
C10H13FN2O4
CAS号:
25526-93-6
分子量:
244.22
MDL编号:
MFCD00056058
UNSPSC代码:
41106305
PubChem化学物质编号:
24862180
NACRES:
NA.22

质量水平

100

方案

97%

表单

solid

mp

176-178 °C (lit.)

储存温度

2-8°C

SMILES字符串

CC1=CN([C@H]2C[C@H](F)[C@@H](CO)O2)C(=O)NC1=O

InChI

1S/C10H13FN2O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1

InChI key

UXCAQJAQSWSNPQ-XLPZGREQSA-N

基因信息

human ... TK2(7084)

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相关类别

应用

具有应用前景的抗病毒试剂，活性类似于其他 3′-脱氧-3′-取代胸苷。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKBK2943V
MKBP5711V
MKBK2943
MKBG8853
MKBD7669

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Sébastien Thureau et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(9), 1543-1550 (2013-08-07)
As the preparation phase of a multicenter clinical trial using (18)F-fluoro-2-deoxy-d-glucose ((18)F-FDG), (18)F-fluoromisonidazole ((18)F-FMISO), and 3'-deoxy-3'-(18)F-fluorothymidine ((18)F-FLT) in non-small cell lung cancer (NSCLC) patients, we investigated whether 18 nuclear medicine centers would score tracer uptake intensity similarly and define hypoxic
Dan J Kadrmas et al.
Physics in medicine and biology, 58(3), 429-449 (2013-01-09)
Rapid multi-tracer PET aims to image two or more tracers in a single scan, simultaneously characterizing multiple aspects of physiology and function without the need for repeat imaging visits. Using dynamic imaging with staggered injections, constraints on the kinetic behavior
Michael S Enslow et al.
Clinical nuclear medicine, 37(9), 854-861 (2012-08-15)
The objective was to compare F-fluorodeoxyglucose (FDG) and F-fluorothymidine (FLT) PET in differentiating radiation necrosis from recurrent glioma. Visual and quantitative analyses were derived from static FDG PET and static and dynamic FLT PET in 15 patients with suspected recurrence
Camilo Garcia et al.
Current opinion in oncology, 24(6), 748-755 (2012-08-24)
(18)F-fluoro-2-deoxy-D-glucose PET-computed tomography (CT) has a major clinical impact in oncology not only for diagnostics but also for staging, response assessment, and relapse detection. However, several other PET tracers are needed for a more complete molecular characterization of cancers which
Bianca A W Hoeben et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(4), 532-540 (2013-01-25)
This prospective study used sequential PET with the proliferation tracer 3'-deoxy-3'-(18)F-fluorothymidine ((18)F-FLT) to monitor the early response to treatment of head and neck cancer and evaluated the association between PET parameters and clinical outcome. Forty-eight patients with head and neck
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