InChI
1S/C9H8N2/c1-2-4-9(5-3-1)11-7-6-10-8-11/h1-8H
SMILES string
c1ccc(cc1)-n2ccnc2
InChI key
SEULWJSKCVACTH-UHFFFAOYSA-N
assay
97%
form
liquid
bp
142 °C/15 mmHg (lit.)
mp
13 °C (lit.)
density
1.14 g/mL at 25 °C (lit.)
Quality Level
General description
1-苯基咪唑是咪唑衍生物。它在虹鳟鱼（虹鳟鱼）肝细胞中诱导 7-乙氧基试卤灵-O-脱乙基酶（EROD）活化。1-苯咪唑的 S（1）→S（0）跃迁已通过共振双光子电离在超声气流膨胀中进行了研究。据报道，1-苯基咪唑是牛脑和 Ghs 垂体细胞钙调蛋白依赖性一氧化氮合酶的抑制剂。
Application
1-苯基咪唑是一种研究其对牛脑一氧化氮合酶对瓜氨酸形成的影响的合适试剂。
signalword
Warning
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Priyadarshini Balaraman et al.
Biochimica et biophysica acta. General subjects, 1863(2), 304-312 (2018-11-06)
The camphor-degrading microorganism, Pseudomonas putida strain ATCC 17453, is an aerobic, gram-negative soil bacterium that uses camphor as its sole carbon and energy source. The genes responsible for the catabolic degradation of camphor are encoded on the extra-chromosomal CAM plasmid.
J A Zijlstra et al.
Mutation research, 198(1), 73-83 (1988-03-01)
The route of administration of a drug is a pharmacological factor to be reckoned with. In Drosophila, a whole-animal object for mutagenicity studies, the way in which a mutagen is applied can also be of crucial importance. In this study
A J Green et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 6(5-6), 523-533 (2001-07-27)
The bioI gene has been sub-cloned and over-expressed in Escherichia coli, and the protein purified to homogeneity. The protein is a cytochrome P450, as indicated by its visible spectrum (low-spin haem iron Soret band at 419 nm) and by the
M R Anari et al.
Chemical research in toxicology, 9(6), 924-931 (1996-09-01)
Organic hydroperoxides are believed to be primarily detoxified in cells by the GSH peroxidase/GSSG reductase system and activated to cytotoxic radical species by non-heme iron. However, organic hydroperoxides seem to be bioactivated by cytochrome P450 (P450) in isolated hepatocytes as
Filippo Monti et al.
Inorganic chemistry, 54(6), 3031-3042 (2015-03-06)
A series of cationic iridium(III) complexes with two carbene-based cyclometalating ligands and five different N^N bipyridine and 1,10-phenanthroline ancillary ligands is presented. For the first time--in the frame of a rarely studied class of bis(heteroleptic) iridium complexes with two carbene-based
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