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Merck
CN

34072

2,4-二溴丁酰氯

technical, ~90% (GC)

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线性分子式:
BrCH2CH2CHBrCOCl
化学文摘社编号:
分子量:
264.34
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4955401
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产品名称

2,4-二溴丁酰氯, technical, ~90% (GC)

InChI

1S/C4H5Br2ClO/c5-2-1-3(6)4(7)8/h3H,1-2H2

SMILES string

ClC(=O)C(Br)CCBr

InChI key

WYZLYWUZERABRL-UHFFFAOYSA-N

grade

technical

assay

~90% (GC)

refractive index

n20/D 1.535

density

2.00 g/mL at 20 °C

functional group

acyl chloride
bromo

storage temp.

2-8°C

Quality Level

Application

2,4-Dibromobutyryl chloride was used in the preparation of:
  • methyl 2,4-dibromobutanoate
  • series of 3-(3, 5-di-tert-butyl-4-hydroxybenzylidene)pyrrolidin-2-ones, anti-inflammatory/analgesic agents
  • α-bromolactam

pictograms

Health hazardCorrosion

signalword

Danger

Hazard Classifications

Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1

supp_hazards

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Preparation of enantiopure 2-acylazetidines and their reactions with chloroformates.
Ma S, et al.
Tetrahedron Letters, 48(2), 269-271 (2007)
H Ikuta et al.
Journal of medicinal chemistry, 30(11), 1995-1998 (1987-11-01)
A series of 3-(3,5-di-tert-butyl-4-hydroxybenzylidene)pyrrolidin-2-ones was synthesized and evaluated as candidate antiinflammatory/analgesic agents as well as dual inhibitors of prostaglandin and leukotriene synthesis. Some compounds that showed dual inhibitory activity were found to possess equipotent antiinflammatory activities to indomethacin, with reduced
Bhooma Raghavan et al.
The Journal of organic chemistry, 71(5), 2151-2154 (2006-02-25)
A concise, stereoselective synthesis of alpha-substituted gamma-lactams is reported. gamma-Lactam scaffolds 2 and 3, possessing an Evans' chiral auxiliary and two types of N substituents, were successfully alkylated with different electrophiles to give alpha-substituted gamma-lactams with reasonable diastereoselectivities. The use

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