推荐产品
检测方案
98%
旋光性
[α]20/D −7.0°, neat
自燃温度
~734 °F
mp
127 °C (dec.) (lit.)
SMILES字符串
NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
InChI
1S/C6H15NO5/c7-1-3(9)5(11)6(12)4(10)2-8/h3-6,8-12H,1-2,7H2/t3-,4+,5+,6+/m0/s1
InChI key
SDOFMBGMRVAJNF-SLPGGIOYSA-N
法规信息
新产品
Qi Qin et al.
CNS neuroscience & therapeutics, 23(2), 162-173 (2016-12-13)
Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most prevalent cause of familial and sporadic Parkinson's disease (PD). Because most pathogenic LRRK2 mutations result in enhanced kinase activity, it suggests that LRRK2 inhibitors may serve as a potential treatment
Ryuto Hara et al.
Neuroscience letters, 728, 134958-134958 (2020-04-13)
We recently showed that the mesolimbic dopaminergic system was tonically suppressed during chronic pain by enhanced corticotropin releasing factor (CRF) signaling within the dorsolateral bed nucleus of the stria terminalis (dlBNST), and that inhibition of intra-dlBNST CRF signaling restored the
Iurii Semenov et al.
Bioelectrochemistry (Amsterdam, Netherlands), 105, 65-71 (2015-05-27)
We tested if picosecond electric pulses (psEP; 190 kV/cm, 500 ps at 50% height), which are much shorter than channel activation time, can activate voltage-gated (VG) channels. Cytosolic Ca(2+) was monitored by Fura-2 ratiometric imaging in GH3 and NG108 cells
Hongxue Zhang et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(1), 807-821 (2020-01-10)
Kv4 pore-forming subunits co-assemble with β-subunits including KChIP2 and DPP6 and the resultant complexes conduct cardiac transient outward K+ current (Ito). Compound NS5806 has been shown to potentate Ito in canine cardiomyocytes; however, its effects on Ito in other species
Karima Ait Ouares et al.
The European journal of neuroscience, 49(1), 6-26 (2018-11-06)
Optogenetics is based on the selective expression of exogenous opsins by neurons allowing experimental control of their electrical activity using visible light. The interpretation of the results of optogenetic experiments is based on the assumption that light stimulation selectively acts
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