337951
槲皮素 水合物
≥95%
别名:
2-(3,4-二羟苯基)-3,5,7-三羟基-4H-1-苯并吡喃-4-一水合物
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关于此项目
经验公式（希尔记法）:
C15H10O7 · xH2O
化学文摘社编号:
分子量:
302.24 (anhydrous basis)
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
204-187-1
MDL number:
Assay:
≥95%
InChI key
OKXFBEYCJRMINR-UHFFFAOYSA-N
InChI
1S/C15H10O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;/h1-5,16-19,21H;1H2
SMILES string
[H]O[H].Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3ccc(O)c(O)c3
assay
≥95%
solubility
DMSO: slightly soluble
functional group
ketone
Quality Level
General description
槲皮素是一种抗锥体和抗利尿剂的化合物。槲皮素是有名的生物类黄酮，有报道表明它能影响体内肿瘤生长。槲皮素对杜氏利什曼原虫的无鞭毛阶段具有杀虫作用。
Application
槲皮素水合物被用作利什曼原虫黄酮醇，用于研究槲皮素、槲皮素和异槲皮苷对来源于亚马孙利什曼原虫的重组精氨酸酶的抑制作用。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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The aim of this study was to develop a new microemulsion formulation for topical application of poorly soluble drug named quercetin. In order to design suitable microemulsion system, the pseudo-ternary phase diagrams of microemulsion systems were constructed at different surfactant/co-surfactant
Hua Chen et al.
Food chemistry, 221, 248-257 (2016-12-17)
The study examined the capability of phytoglycogen (PG) to improve the water solubility of quercetin (QC). PG-QC formulations were prepared by mixing a QC ethanol solution with a PG aqueous solution followed with vacuum drying of the supernatant. PG-QC formulations
Tumour response to quercetin, a bioflavonoid with some promises in therapies.
Indap MA, et al.
Indian Journal of Pharmaceutical Sciences, 68(5), 570-570 (2006)
Shengfeng Peng et al.
Journal of agricultural and food chemistry, 67(26), 7506-7511 (2019-06-12)
The poor water solubility and oral bioavailability of many lipophilic polyphenols can be improved through the use of colloidal delivery systems. In this study, a pH-driven method was used to encapsulate curcumin, quercetin, and resveratrol within nanoliposomes. This method is
Edson Roberto da Silva et al.
Experimental parasitology, 130(3), 183-188 (2012-02-14)
Polyamine biosynthesis enzymes are promising drug targets for the treatment of leishmaniasis, Chagas' disease and African sleeping sickness. Arginase, which is a metallohydrolase, is the first enzyme involved in polyamine biosynthesis and converts arginine into ornithine and urea. Ornithine is
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