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Merck
CN

333662

Sigma-Aldrich

1H-1,2,3-三氮唑

97%

别名:

2,3-二氮杂吡咯, 2H-1,2,3-三唑, 三唑, 三氮唑, 三氮杂环戊二烯

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About This Item

经验公式(希尔记法):
C2H3N3
CAS号:
分子量:
69.07
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

97%

表单

liquid

折射率

n20/D 1.498 (lit.)

沸点

203 °C/752 mmHg (lit.)

mp

23-25 °C (lit.)

密度

1.192 g/mL at 25 °C (lit.)

SMILES字符串

c1c[nH]nn1

InChI

1S/C2H3N3/c1-2-4-5-3-1/h1-2H,(H,3,4,5)

InChI key

QWENRTYMTSOGBR-UHFFFAOYSA-N

一般描述

2 H -1,2,3-三唑是 1 H -1,2,3-三唑的互变异构体。1H-1,2,3-三唑通过分子间质子转移机制有效地促进了质子在聚合物电解质膜中的传导。

应用

  • 结晶框架材料:对三唑羧酸配体的研究已经证明其在智能晶体框架材料中的应用,特别是在荧光传感和对硝基苯酚的催化还原方面,说明其在化学传感和环境应用中具有实用性(Lv et al., 2023)。
  • PXR受体调节:1H-1,2,3-三唑-4-羧酰胺已被优化为PXR受体的强效选择性逆激动剂和拮抗剂,对受体特异性药物的设计具有参考价值(Li et al., 2022)。
  • 大规模合成:利用改良的Sakai反应大规模合成Notum抑制剂说明H-1,2,3-三唑在生化试剂生产中很重要,对于医学研究和药物开发是必不可少的(Atkinson et al., 2022)。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

224.6 °F - closed cup

闪点(°C)

107 °C - closed cup

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Zhen Zhou et al.
Journal of the American Chemical Society, 127(31), 10824-10825 (2005-08-04)
We report 1H-1,2,3-triazole as an active group to dramatically enhance proton conduction in a polymer electrolyte membrane (PEM). The conductivities of a poly(4-vinyl-1H-1,2,3-triazole) membrane without any acidic dopants are about 105 times greater than those of poly(4-vinylimidazole) in dry air
Atul Bhardwaj et al.
Nature communications, 8(1), 1-1 (2017-02-25)
Cyclooxygenase-2 isozyme is a promising anti-inflammatory drug target, and overexpression of this enzyme is also associated with several cancers and neurodegenerative diseases. The amino-acid sequence and structural similarity between inducible cyclooxygenase-2 and housekeeping cyclooxygenase-1 isoforms present a significant challenge to
Amanda R Robinson et al.
PLoS pathogens, 8(2), e1002516-e1002516 (2012-02-22)
The Epstein-Barr virus (EBV) latent-lytic switch is mediated by the BZLF1 immediate-early protein. EBV is normally latent in memory B cells, but cellular factors which promote viral latency specifically in B cells have not been identified. In this report, we
Fong-Fong Chu et al.
World journal of gastroenterology, 22(46), 10158-10165 (2016-12-29)
To test whether Nox1 plays a role in typhlitis induced by Salmonella enterica serovar Typhimurium (S. Tm) in a mouse model. Eight-week-old male wild-type (WT) and Nox1 knockout (KO) C57BL6/J (B6) mice were administered metronidazole water for 4 d to
Marylou C Machingura et al.
Journal of experimental botany, 68(14), 3879-3890 (2017-06-22)
The supply of inorganic carbon (Ci) at the site of fixation by Rubisco is a key parameter for efficient CO2 fixation in aquatic organisms including the green alga, Chlamydomonas reinhardtii. Chlamydomonas reinhardtii cells, when grown on limiting CO2, have a

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