333131
N,N′-二(2-氨乙基)-1,3-丙二胺
97%
别名:
1,3-双（2-氨基乙基氨基）丙烷, 1,4,8,11-四氮杂十一烷, 1,9-二氨基-3,7-二氮杂壬烷, 2,3,2-三乙烯四胺, 3,7-二氮杂-1,9-二氨基壬烷, 3,7-二氮杂壬烷-1,9-二胺, N,N′-双(2-氨基乙基)丙烷-1,3-二胺, N1,N3-双(2-氨基乙基)-1,3-丙二胺, 乙烯(三亚甲基)乙烯四胺
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所有图片(1)
About This Item
线性分子式:
H2NCH2CH2NH(CH2)3NHCH2CH2NH2
CAS号:
分子量:
160.26
Beilstein:
1742732
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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质量水平
方案
97%
表单
liquid
折射率
n20/D 1.494 (lit.)
沸点
142-145 °C/8 mmHg (lit.)
密度
0.96 g/mL at 25 °C (lit.)
官能团
amine
SMILES字符串
NCCNCCCNCCN
InChI
1S/C7H20N4/c8-2-6-10-4-1-5-11-7-3-9/h10-11H,1-9H2
InChI key
UWMHHZFHBCYGCV-UHFFFAOYSA-N
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一般描述
N,N′-双（2-氨基乙基）-1,3-丙二胺是高亲和力的 Cu（II）螯合剂。它通过在人早幼粒细胞白血病细胞系（HL-60）中引起细胞铜缺乏而抑制线粒体细胞色素 C 氧化酶。
应用
N,N′-双（2-氨基乙基）-1,3-丙二胺用于研究编码铜的大肠埃希氏菌超氧化物歧化酶基因的调控。
警示用语：
Danger
危险声明
危险分类
Skin Corr. 1B
储存分类代码
8A - Combustible corrosive hazardous materials
WGK
WGK 3
闪点(°F)
230.0 °F - closed cup
闪点(°C)
110 °C - closed cup
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Zhouxi Wang et al.
BMC bioinformatics, 14 Suppl 3, S13-S13 (2013-03-27)
The prediction of biochemical function from the 3D structure of a protein has proved to be much more difficult than was originally foreseen. A reliable method to test the likelihood of putative annotations and to predict function from structure would
A S Gort et al.
Molecular microbiology, 32(1), 179-191 (1999-04-27)
The discovery of superoxide dismutase (CuZnSOD) within the periplasms of several Gram-negative pathogens suggested that this enzyme evolved to protect cells from exogenous sources of superoxide, such as the oxidative burst of phagocytes. However, its presence in some non-pathogenic bacteria
Laura J Raymond et al.
Experimental biology and medicine (Maywood, N.J.), 229(9), 885-894 (2004-09-25)
Cytochrome c oxidase (CCO) is the Cu-dependent, terminal respiratory complex of the mitochondrial electron transport chain. Inhibition of CCO can promote oxidative stress by increasing mitochondrial production of reactive oxygen species (ROS). Because mitochondria have an important role in apoptosis
Changyong Cheng et al.
Journal of medical microbiology, 62(Pt 6), 813-821 (2013-03-23)
The foodborne pathogen Listeria monocytogenes is able to colonize the human and animal intestinal tracts and subsequently crosses the intestinal barrier, causing systemic infection. For successful establishment of infection, L. monocytogenes must survive and adapt to the low pH environment
Yongxia Guo et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(20), 8284-8289 (2013-04-25)
Genetic studies in Arabidopsis implicate an α/β-hydrolase, KARRIKIN-INSENSITIVE 2 (KAI2) as a receptor for karrikins, germination-promoting butenolide small molecules found in the smoke of burned plants. However, direct biochemical evidence for the interaction between KAI2 and karrikin and for the
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