333131
N,N′-二(2-氨乙基)-1,3-丙二胺
97%
别名:
1,3-双（2-氨基乙基氨基）丙烷, 1,4,8,11-四氮杂十一烷, 1,9-二氨基-3,7-二氮杂壬烷, 2,3,2-三乙烯四胺, 3,7-二氮杂-1,9-二氨基壬烷, 3,7-二氮杂壬烷-1,9-二胺, N,N′-双(2-氨基乙基)丙烷-1,3-二胺, N1,N3-双(2-氨基乙基)-1,3-丙二胺, 乙烯(三亚甲基)乙烯四胺
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关于此项目
线性分子式:
H2NCH2CH2NH(CH2)3NHCH2CH2NH2
化学文摘社编号:
分子量:
160.26
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
225-254-1
Beilstein/REAXYS Number:
1742732
MDL number:
产品名称
N,N′-二(2-氨乙基)-1,3-丙二胺, 97%
InChI key
UWMHHZFHBCYGCV-UHFFFAOYSA-N
InChI
1S/C7H20N4/c8-2-6-10-4-1-5-11-7-3-9/h10-11H,1-9H2
SMILES string
NCCNCCCNCCN
assay
97%
form
liquid
refractive index
n20/D 1.494 (lit.)
bp
142-145 °C/8 mmHg (lit.)
density
0.96 g/mL at 25 °C (lit.)
functional group
amine
Quality Level
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Application
N,N′-双（2-氨基乙基）-1,3-丙二胺用于研究编码铜的大肠埃希氏菌超氧化物歧化酶基因的调控。
General description
N,N′-双（2-氨基乙基）-1,3-丙二胺是高亲和力的 Cu（II）螯合剂。它通过在人早幼粒细胞白血病细胞系（HL-60）中引起细胞铜缺乏而抑制线粒体细胞色素 C 氧化酶。
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
230.0 °F - closed cup
flash_point_c
110 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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The prediction of biochemical function from the 3D structure of a protein has proved to be much more difficult than was originally foreseen. A reliable method to test the likelihood of putative annotations and to predict function from structure would
A S Gort et al.
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The discovery of superoxide dismutase (CuZnSOD) within the periplasms of several Gram-negative pathogens suggested that this enzyme evolved to protect cells from exogenous sources of superoxide, such as the oxidative burst of phagocytes. However, its presence in some non-pathogenic bacteria
Laura J Raymond et al.
Experimental biology and medicine (Maywood, N.J.), 229(9), 885-894 (2004-09-25)
Cytochrome c oxidase (CCO) is the Cu-dependent, terminal respiratory complex of the mitochondrial electron transport chain. Inhibition of CCO can promote oxidative stress by increasing mitochondrial production of reactive oxygen species (ROS). Because mitochondria have an important role in apoptosis
Changyong Cheng et al.
Journal of medical microbiology, 62(Pt 6), 813-821 (2013-03-23)
The foodborne pathogen Listeria monocytogenes is able to colonize the human and animal intestinal tracts and subsequently crosses the intestinal barrier, causing systemic infection. For successful establishment of infection, L. monocytogenes must survive and adapt to the low pH environment
Ana C Scorsetti et al.
Revista de biologia tropical, 60(2), 833-841 (2013-07-31)
Tolypocladium cylindrosporum is an entomopathogenic fungi that has been studied as a biological control agent against insects of several orders. The fungus has been isolated from the soil as well as from insects of the orders Coleoptera, Lepidoptera, Diptera and
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