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线性分子式:
HOOCCH(NH2)(CH2)3CH(NH2)COOH
化学文摘社编号:
分子量:
190.20
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352103
EC Number:
209-524-6
MDL number:
Beilstein/REAXYS Number:
1787719
产品名称
2,6-二氨基庚二酸, ≥95.0% (NT)
InChI
1S/C7H14N2O4/c8-4(6(10)11)2-1-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)
SMILES string
NC(CCCC(N)C(O)=O)C(O)=O
InChI key
GMKMEZVLHJARHF-UHFFFAOYSA-N
assay
≥95.0% (NT)
form
powder
reaction suitability
reaction type: solution phase peptide synthesis
mp
~295 °C (dec.) (lit.)
application(s)
peptide synthesis
Quality Level
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Application
2,6-二氨基庚二酸(2,6-DAP)可作为建构单元,合成三肽 ,和 γ-谷氨酰基二氨基庚二酸衍生物。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Structure- activity relationships in nucleotide oligomerization domain 1 (Nod1) agonistic γ-glutamyldiaminopimelic acid derivatives
Agnihotri G, et al.
Journal of Medicinal Chemistry, 54(5), 1490-1510 (2011)
A new stereocontrolled synthesis of uncommon tripeptides derived from 2, 6-diaminopimelic acid (2, 6-DAP)
Paradisi F, et al.
Tetrahedron Asymmetry, 12(23), 3319-3324 (2001)
Soji Iida et al.
International journal of systematic and evolutionary microbiology, 55(Pt 5), 1871-1876 (2005-09-17)
The taxonomic positions of two clinically isolated actinomycetes were established using a polyphasic approach. The two strains, IFM 10032(T), isolated from ear discharge of a 28-year-old Japanese female patient with external otitis, and IFM 10148, isolated from pleural fluid of
Jian Zhang et al.
International journal of systematic and evolutionary microbiology, 63(Pt 5), 1776-1781 (2012-09-04)
A bacterial strain, designated D75(T), was isolated from the rhizosphere soil of Catalpa speciosa. Phylogenetic analysis based on the complete 16S rRNA gene sequence revealed that strain D75(T) was a member of the genus Paenibacillus. High levels of 16S rRNA
Lilian Hor et al.
Biochimie, 95(10), 1949-1953 (2013-07-11)
DAP epimerase is the penultimate enzyme in the lysine biosynthesis pathway. The most versatile assay for DAP epimerase catalytic activity employs a coupled DAP epimerase-DAP dehydrogenase enzyme system with a commercial mixture of DAP isomers as substrate. DAP dehydrogenase converts
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