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主要文件

安全信息

329231

Sigma-Aldrich

4,5-二甲氧基-2-硝基苯甲酸

99%

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100 G
¥1,877.08

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100 G
¥1,877.08

About This Item

线性分子式:
O2NC6H2(OCH3)2CO2H
CAS号:
分子量:
227.17
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

¥1,877.08


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质量水平

方案

99%

mp

195-197 °C (lit.)

官能团

carboxylic acid
nitro

SMILES字符串

COc1cc(C(O)=O)c(cc1OC)[N+]([O-])=O

InChI

1S/C9H9NO6/c1-15-7-3-5(9(11)12)6(10(13)14)4-8(7)16-2/h3-4H,1-2H3,(H,11,12)

InChI key

WWCMFGBGMJAJRX-UHFFFAOYSA-N

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422916391999468983
Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

-

mp

195-197 °C (lit.)

mp

146-148 °C (lit.)

mp

125-130 °C (lit.)

mp

165-167 °C (lit.)

一般描述

4,5-Dimethoxy-2-nitrobenzoic acid is a nitroaromatic compound.[1]

应用

4,5-Dimethoxy-2-nitrobenzoic acid was used in the synthesis of 4,5-dimethoxy-2-nitrobenzamide[2] and 6,7-dimethoxyquinazoline derivatives.[3]

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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    R K Narla et al.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 4(6), 1405-1414 (1998-06-17)
    The novel quinazoline derivative 4-(3'-bromo-4'-hydroxylphenyl)-amino-6,7-dimethoxyquinazoline (WHI-P154) exhibited significant cytotoxicity against U373 and U87 human glioblastoma cell lines, causing apoptotic cell death at micromolar concentrations. The in vitro antiglioblastoma activity of WHI-P154 was amplified > 200-fold and rendered selective by conjugation
    J Navrátilová et al.
    Folia microbiologica, 49(5), 613-615 (2005-02-11)
    Two bacterial strains were isolated from forest soil by selective enrichment of the mineral medium containing 4-nitropyrocatechol as the sole carbon and energy source. Both strains could utilize 4-nitropyrocatechol and 5-nitroguaiacol. Degradation of 5-nitroguaiacol and stoichiometric release of nitrites was
    P A Goodman et al.
    The Journal of biological chemistry, 273(28), 17742-17748 (1998-07-04)
    Exposure of B-lineage lymphoid cells to ionizing radiation induces an elevation of c-jun proto-oncogene mRNA levels. This signal is abrogated by protein-tyrosine kinase (PTK) inhibitors, indicating that activation of an as yet unidentified PTK is mandatory for radiation-induced c-jun expression.

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