329061
2-巯基吡啶-N-氧化物 钠盐
95%
别名:
1-Oxo-2-pyridinethiol sodium salt, 2-Pyridinethiol N-oxide sodium salt, Sodium (2-pyridylthio-1-oxide), Sodium 2-mercaptopyridine 1-oxide, Sodium 2-mercaptopyridine N-oxide
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所有图片(2)
About This Item
经验公式（希尔记法）:
C5H4NNaOS
CAS号:
分子量:
149.15
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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质量水平
方案
95%
溶解性
water: soluble 0.5 g/10 mL, clear, colorless to light yellow
SMILES字符串
O.[O-][n+]1ccccc1S[Na]
InChI
1S/C5H5NOS.Na/c7-6-4-2-1-3-5(6)8;/h1-4,8H;/q;+1/p-1
InChI key
WNGMMIYXPIAYOB-UHFFFAOYSA-M
一般描述
2-Mercaptopyridine N-oxide acts as labelling agent during indium-111 labelling of human platelets. It acts as bioactive ligand and forms palladium and platinum complexes, which were tested as potential antitrypanosomal agents.
应用
2-巯基吡啶-N-氧化物的化学作用，请参见 Aldrichimica Acta。
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1
靶器官
Nervous system
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Y Isaka et al.
European journal of nuclear medicine, 18(5), 326-331 (1991-01-01)
Human platelets were labelled in the absence or presence of plasma using indium-111 labelled oxine sulphate, tropolone or 2-mercaptopyridine-N-oxide (MPO). Under in vitro and in vivo conditions, platelet functions were evaluated by measuring their aggregability, survival, recovery and early distribution.
Marisol Vieites et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 13(5), 723-735 (2008-03-07)
In the search for new therapeutic tools against Chagas disease (American trypanosomiasis) palladium and platinum complexes of the bioactive ligand pyridine-2-thiol N-oxide were exhaustively characterized and evaluated in vitro. Both complexes showed high in vitro growth inhibition activity (IC(50) values
Aldrichimica Acta, 20, 35-35 (1987)
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