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Merck
CN

317276

Sigma-Aldrich

氯乙醛 溶液

~55 wt. % in H2O

别名:

α-氯乙醛, 2-氯-1-乙醛, 2-氯乙醛, 一氯乙醛

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About This Item

线性分子式:
ClCH2CHO
CAS号:
分子量:
78.50
Beilstein:
1071226
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

表单

liquid

质量水平

浓度

~55 wt. % in H2O

折射率

n20/D 1.4036

密度

1.236 g/mL at 25 °C

官能团

aldehyde
chloro

SMILES字符串

[H]C(=O)CCl

InChI

1S/C2H3ClO/c3-1-2-4/h2H,1H2

InChI key

QSKPIOLLBIHNAC-UHFFFAOYSA-N

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应用

氯乙醛溶液可用于合成:
  • 核苷酸衍生物。
  • 通过Hantzsch反应合成2,3-双取代的吡咯。
  • 氨基四氢萘酮哌嗪支架,作为强效MCH-R1拮抗剂。

警示用语:

Danger

危险分类

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Carc. 2 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

143.6 °F - closed cup

闪点(°C)

62 °C - closed cup

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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分析证书(COA)

Lot/Batch Number

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Determination of leukocyte DNA 6-thioguanine nucleotide levels by high-performance liquid chromatography with fluorescence detection
Olesen KM, et al.
Journal of Chromatography. B, Biomedical Applications, 864(1-2), 149-155 (2008)
The efficacy and cardiac evaluation of aminomethyl tetrahydronaphthalene ketopiperazines: a novel class of potent MCH-R1 antagonists
Mendez-Andino JL, et al.
Bioorganic & Medicinal Chemistry, 15(5), 2092-2105 (2007)
Stephanie L MacAllister et al.
Chemico-biological interactions, 202(1-3), 259-266 (2012-12-12)
Cyclophosphamide and ifosfamide are two commonly used DNA-alkylating agents in cancer chemotherapy that undergo biotransformation to several toxic and non-toxic metabolites, including acrolein and chloroacetaldehyde (CAA). Acrolein and CAA toxicities occur by several different mechanisms, including ROS formation and protein
V Nagarajavel et al.
The Journal of biological chemistry, 282(32), 23622-23630 (2007-06-16)
H-NS inhibits transcription by forming repressing nucleoprotein complexes next to promoters. We investigated repression by binding of H-NS within the transcription unit using the bgl and proU operons. Repression of both operons requires a downstream regulatory element (DRE) in addition

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