309346
L-谷氨酸二乙酯 盐酸盐
97%
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关于此项目
线性分子式:
C2H5OCOCH2CH2CH(NH2)COOC2H5 · HCl
化学文摘社编号:
分子量:
239.70
UNSPSC Code:
12352209
NACRES:
NA.22
PubChem Substance ID:
EC Number:
214-270-4
Beilstein/REAXYS Number:
3597595
MDL number:
InChI key
WSEQLMQNPBNMSL-FJXQXJEOSA-N
InChI
1S/C9H17NO4.ClH/c1-3-13-8(11)6-5-7(10)9(12)14-4-2;/h7H,3-6,10H2,1-2H3;1H/t7-;/m0./s1
SMILES string
Cl[H].CCOC(=O)CC[C@H](N)C(=O)OCC
assay
97%
optical activity
[α]18/D +22°, c = 1 in H2O
reaction suitability
reaction type: solution phase peptide synthesis
mp
108-110 °C (lit.)
application(s)
peptide synthesis
Quality Level
Application
L-Glutamic acid diethyl ester hydrochloride can be used in the synthesis of:
- Oligo(γ-ethyl L-glutamate) via oligomerization catalyzed by papain.
- L-glutamic acid based dendritic compounds.
- Poly(α-peptide) by polymerization and copolymerization in the presence of protease catalysts.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Ultrasound induced formation of organogel from a glutamic dendron
Li Y, et al.
Tetrahedron, 63(31), 7468-7473 (2007)
M G Matheus et al.
Psychopharmacology, 132(1), 14-18 (1997-07-01)
Microinjections of glutamate into the dorsal periaqueductal grey (DPAG) of rats induce flight behavior, and blockade of glutamate NMDA receptors in the same region increases exploratory behavior of rats tested on the elevated plus maze. To investigate a possible role
Inhibition of cocaine intoxication by excitatory amino acid receptor antagonists.
R W Rockhold et al.
Annals of the New York Academy of Sciences, 648, 335-337 (1992-05-11)
Rapid regioselective oligomerization of L-glutamic acid diethyl ester catalyzed by papain
Li G, et al.
Macromolecules, 39(23), 7915-7921 (2006)
F Barnabi et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 281(5), R1665-R1674 (2001-10-20)
Neurotransmitters relaying ascending visceral information were examined by comparing the response of neurons in the insular cortex to vagal stimulation (0.8 Hz, 2 mA) before and after neurotransmitter antagonist injections (200 nl) in the ventroposterior parvocellular nucleus of the thalamus
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