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Merck
CN

309346

Sigma-Aldrich

L-谷氨酸二乙酯 盐酸盐

97%

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About This Item

线性分子式:
C2H5OCOCH2CH2CH(NH2)COOC2H5 · HCl
CAS号:
分子量:
239.70
Beilstein:
3597595
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

97%

旋光性

[α]18/D +22°, c = 1 in H2O

反应适用性

reaction type: solution phase peptide synthesis

mp

108-110 °C (lit.)

应用

peptide synthesis

SMILES字符串

Cl[H].CCOC(=O)CC[C@H](N)C(=O)OCC

InChI

1S/C9H17NO4.ClH/c1-3-13-8(11)6-5-7(10)9(12)14-4-2;/h7H,3-6,10H2,1-2H3;1H/t7-;/m0./s1

InChI key

WSEQLMQNPBNMSL-FJXQXJEOSA-N

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应用

L-Glutamic acid diethyl ester hydrochloride can be used in the synthesis of:
  • Oligo(γ-ethyl L-glutamate) via oligomerization catalyzed by papain.
  • L-glutamic acid based dendritic compounds.
  • Poly(α-peptide) by polymerization and copolymerization in the presence of protease catalysts.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Rapid regioselective oligomerization of L-glutamic acid diethyl ester catalyzed by papain
Li G, et al.
Macromolecules, 39(23), 7915-7921 (2006)
Ultrasound induced formation of organogel from a glutamic dendron
Li Y, et al.
Tetrahedron, 63(31), 7468-7473 (2007)
T Kubo et al.
Brain research, 616(1-2), 311-314 (1993-07-09)
Neonatal Wistar rats were subcutaneously injected with 0.1, 1, or 2 mg/g b.wt. of monosodium glutamate (MSG) at 1, 3, 5, 7, and 9 days after birth. The animals were observed for degeneration of pyramidal cells in the hippocampus. The
Inhibition of cocaine intoxication by excitatory amino acid receptor antagonists.
R W Rockhold et al.
Annals of the New York Academy of Sciences, 648, 335-337 (1992-05-11)
Manoel Jorge Nobre et al.
Life sciences, 71(25), 2961-2972 (2002-10-18)
Gradual increases in the electrical stimulation of the inferior colliculus produces progressive aversive responses from vigilance, through freezing, until escape. These responses are probably mediated by excitatory amino acids (EAA) mechanisms as microinjection of glutamate into the inferior colliculus can

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