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Merck
CN

303526

Sigma-Aldrich

2-氨基-5-溴嘧啶

98%

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经验公式(希尔记法):
C4H4BrN3
CAS号:
分子量:
174.00
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

98%

形式

solid

mp

241-243 °C (lit.)

SMILES字符串

Nc1ncc(Br)cn1

InChI

1S/C4H4BrN3/c5-3-1-7-4(6)8-2-3/h1-2H,(H2,6,7,8)

InChI key

UHRHPPKWXSNZLR-UHFFFAOYSA-N

一般描述

Crystal structure of 2-amino-5-bromopyrimidine was studied.

应用

2-Amino-5-bromopyrimidine was employed:
  • in synthesis of pyridine, pyrimidine and pyridinone C-nucleoside phosphoramidites
  • in synthesis of 2-phthalimido-5-bromopyrimidine
  • as intermediate for the preparation of sulfanilamides and amino acids containing the pyrimidine ring system. The products are potential antiviral agents

象形图

Exclamation markEnvironment

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

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Structure of 2-amino-5-bromopyrimidine.
Watton HLL, et al.
Acta Crystallographica Section C, Crystal Structure Communications, 44(10), 1857-1858 (1988)
Journal of Chemical Education, 62, 905-905 (1985)
Jun Lu et al.
The Journal of organic chemistry, 74(21), 8021-8030 (2009-10-02)
In the structures of the HDV ribozyme a cytosine nucleobase resides at the active site poised to participate directly in catalysis. Defining the functional role of the nucleobase requires nucleoside analogues that perturb the functional groups in a strategic manner.
Self-assembly of 1-and 2-dimensional multicompartmental arrays via the 2-aminopyrimidine H-bonding motif and selective guest inclusion.
Krische MJ, et al.
Tetrahedron, 56(36), 6701-6706 (2000)

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