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Merck
CN

300373

Sigma-Aldrich

2,3-二溴丙酰氯

97%

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About This Item

线性分子式:
BrCH2CHBrCOCl
CAS号:
分子量:
250.32
Beilstein:
1749801
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:

方案

97%

表单

liquid

折射率

n20/D 1.542 (lit.)

沸点

191-193 °C (lit.)

密度

2.181 g/mL at 25 °C (lit.)

SMILES字符串

ClC(=O)C(Br)CBr

InChI

1S/C3H3Br2ClO/c4-1-2(5)3(6)7/h2H,1H2

InChI key

HWKWYDXHMQQDQJ-UHFFFAOYSA-N

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应用

2,3-Dibromopropionyl chloride was used in synthesis of:
  • series of 2,3-diaminopropionanilides
  • enantiomers of 1,4-dideoxy-1,4-iminolyxitol and 1,4-dideoxy-1,4-iminoribitol
  • acromelic acid A

象形图

CorrosionExclamation mark

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

靶器官

Respiratory system

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 3

闪点(°F)

150.8 °F - closed cup

闪点(°C)

66 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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分析证书(COA)

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Chiral synthesis of both enantiomers of 1, 4-dideoxy-1, 4-immolyxitol and 1, 4-dideoxy-1, 4-iminoribitol.
Takano S, et al.
Tetrahedron Asymmetry, 3(6), 681-684 (1992)
P A Tenthorey et al.
Journal of medicinal chemistry, 24(9), 1059-1063 (1981-09-01)
A series of 2,3-diaminopropionanilides was synthesized by acylation of mono- and disubstituted aniline derivatives with 2,3-dibromopropionyl chloride and subsequent amination with the appropriate secondary amines. The target compounds were evaluated in mice for antiarrhythmic efficacy against chloroform-induced tachycardia and for
Concise enantioselective synthesis of acromelic acid A.
Takano S, et al.
Journal of the American Chemical Society, 109(18), 5523-5524 (1987)

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