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Merck
CN

296783

Sigma-Aldrich

1H-苯并咪唑-5-羧酸

96%

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About This Item

经验公式(希尔记法):
C8H6N2O2
CAS号:
分子量:
162.15
MDL编号:
UNSPSC代码:
12352100
eCl@ss:
32151902
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

96%

mp

>300 °C (lit.)

官能团

carboxylic acid

SMILES字符串

OC(=O)c1ccc2[nH]cnc2c1

InChI

1S/C8H6N2O2/c11-8(12)5-1-2-6-7(3-5)10-4-9-6/h1-4H,(H,9,10)(H,11,12)

InChI key

COYPLDIXZODDDL-UHFFFAOYSA-N

一般描述

Drug-specific monoclonal antibodies were produced against the very small drug hapten, 5-benzimidazolecarboxylic acid.

应用

5-Benzimidazolecarboxylic acid has been used in the preparation of:
  • 1H-benzoimidazole-5-carboxylic acid benzotriazol-1-yl ester
  • piperidin-1-yl(1-m-tolyl-1H-benzo[d]imidazol-5-yl)methanone

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品

从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

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访问文档库

Ajit Jadhav et al.
Probe Reports from the NIH Molecular Libraries Program, 2010 Mar 4 (Updated 2011 Mar 11) (2011-07-08)
15-hydroxyprostaglandin dehydrogenase (15-PGDH; HPGD) is the key enzyme for the inactivation of prostaglandins, and thus regulates processes such as inflammation or proliferation. The anabolic pathways of prostaglandins are well-characterized, especially with respect to regulation of the cyclooxygenase (COX) enzymes. In
E S Medlock et al.
The Anatomical record, 207(1), 31-41 (1983-09-01)
Mouse fetal liver was studied ultrastructurally to identify and characterize the developing hepatic parenchyma or prehepatocyte which may be responsible for producing the liver hemopoietic environment. It was observed that as the liver develops, there is close association of endodermal
E Moran et al.
Journal of immunological methods, 271(1-2), 65-75 (2002-11-26)
Drug-specific monoclonal antibodies (MAbs) were produced against the very small drug hapten (162.15 Da), 5-benzimidazolecarboxylic acid, an analogue of 2-(4-Thiazolyl)benzimidazole (TBZ) but lacking the thiol group. TBZ is widely used as a broad-spectrum anthelmintic in various animal species and humans
Xiaofei Chen et al.
Biomaterials science, 3(6), 870-878 (2015-07-30)
Herein, hyperbranched poly(ethylene glycol)-based supramolecular nanoparticles with pH-sensitive properties were designed and used for targeted drug delivery. Via host-guest recognition between benzimidazole anchored poly(ethylene glycol)-hyperbranched polyglycerol (PEG-HPG-BM) and folic acid modified CD (FA-CD), targeted supramolecular nanoparticles (TSNs) were fabricated. At

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