质量水平
检测方案
≥98.0% (T)
形式
solid
mp
~180 °C (dec.)
溶解性
dioxane: 1 g/10 mL, clear, colorless (hot)
SMILES字符串
OS(=O)(=O)NC1CCCCC1
InChI
1S/C6H13NO3S/c8-11(9,10)7-6-4-2-1-3-5-6/h6-7H,1-5H2,(H,8,9,10)
InChI key
HCAJEUSONLESMK-UHFFFAOYSA-N
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一般描述
The N-cyclohexylsulfamic acid salts of well−known therapeutic agents were prepared.
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Modification of physical properties of certain antitussive and antihistaminic agents by formation of N-cyclohexylsulfamate salts.
J A CAMPBELL et al.
Journal of pharmaceutical sciences, 51, 931-934 (1962-10-01)
Lin Yi et al.
Analytical and bioanalytical chemistry, 386(3), 666-674 (2006-05-26)
Characterizing the biological effects of metabolic transformations (or biotransformation) is one of the key steps in developing safe and effective pharmaceuticals. Sulfate conjugation, one of the major phase II biotransformations, is the focus of this study. While this biotransformation typically
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