295353
六氟丙酮
97%
别名:
六氟-2-丙酮
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关于此项目
线性分子式:
(CF3)2CO
化学文摘社编号:
分子量:
166.02
UNSPSC Code:
12142100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
211-676-3
Beilstein/REAXYS Number:
607236
MDL number:
Assay:
97%
InChI key
VBZWSGALLODQNC-UHFFFAOYSA-N
InChI
1S/C3F6O/c4-2(5,6)1(10)3(7,8)9
SMILES string
FC(F)(F)C(=O)C(F)(F)F
vapor density
1.65 (vs air)
vapor pressure
4525 mmHg ( 21.1 °C)
assay
97%
bp
−26 °C (lit.)
mp
−129 °C (lit.)
Packaging
Legal Information
Aldrich is a registered trademark of Sigma-Aldrich Co. LLC
Sure/Pac is a trademark of Sigma-Aldrich Co. LLC
signalword
Danger
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Press. Gas Compr. Gas - Repr. 1B - Skin Corr. 1B
supp_hazards
存储类别
2A - Gases
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Faceshields, Gloves, Goggles, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
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The light-harvesting 1 reaction center (LH1-RC) complex in the thermophilic purple sulfur bacterium Thermochromatium (Tch.) tepidum binds Ca ions as cofactors, and Ca-binding is largely involved in its characteristic Q
Hexafluoroacetone as protecting and activating reagent: new routes to amino, hydroxy, and mercapto acids and their application for peptide and glyco- and depsipeptide modification.
Jan Spengler et al.
Chemical reviews, 106(11), 4728-4746 (2006-11-10)
Fufeng Liu et al.
ACS chemical neuroscience, 10(1), 588-598 (2018-10-20)
The fibrillogenesis of amyloid-β protein (Aβ) is considered a crucial factor in the pathogenesis of Alzheimer's disease (AD). Hence, inhibiting Aβ fibrillogenesis is regarded as the primary therapeutic strategy for the prevention and treatment of AD. However, the development of
"Teflon-coated peptides": hexafluoroacetone trihydrate as a structure stabilizer for peptides.
R Rajan et al.
Biopolymers, 42(2), 125-128 (1997-08-01)
Stefania Albrizio et al.
Journal of medicinal chemistry, 45(4), 762-769 (2002-02-08)
CCK-15, a peptide derived from the 115-membered CCK preprohormone, was the object of a comparative conformational analysis by NMR spectroscopy and molecular modeling methods. NMR data in several solvents demonstrate that the propensity of the peptide to fold into a
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