推荐产品
方案
97%
mp
278-280 °C (lit.)
官能团
ester
SMILES字符串
CC1=C(C)c2ccc(O)c(C)c2OC1=O
InChI
1S/C12H12O3/c1-6-7(2)12(14)15-11-8(3)10(13)5-4-9(6)11/h4-5,13H,1-3H3
InChI key
GNBLUSRSAGXTJN-UHFFFAOYSA-N
一般描述
7-Hydroxy-3,4,8-trimethylcoumarin is an inhibitor of melanin production.
应用
7-Hydroxy-3,4,8-trimethylcoumarin has been used:
- to investigate the effect of melanin inhibiting compounds on mycelial pigmentation of Aspergillus bridgeri grown on potato dextrose agar
- in the preparation of 7-ethynyl-3,4,8-trimethylcoumarin
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
Chemical research in toxicology, 25(5), 1047-1057 (2012-03-27)
To discover new selective mechanism-based P450 inhibitors, eight 7-ethynylcoumarin derivatives were prepared through a facile two-step synthetic route. Cytochrome P450 activity assays indicated that introduction of functional groups in the backbone of coumarin could enhance the inhibition activities toward P450s
Letters in applied microbiology, 53(3), 350-358 (2011-07-06)
The aim of the study is to isolate and characterize a melanin pigment from a new strain of Aspergillus bridgeri isolated from rhizosphere soil of Eucalyptus tree and to investigate its antioxidant activity. The extracellular pigment was alkali soluble, acid-resistant
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