291552
6-甲氧基-1,2,3,4-四氢-9-H-吡啶[3,4-b]吲哚
97%
别名:
6-甲氧基-1,2,3,4-四氢-β-咔啉
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关于此项目
经验公式（希尔记法）:
C12H14N2O
化学文摘社编号:
分子量:
202.25
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
InChI
1S/C12H14N2O/c1-15-8-2-3-11-10(6-8)9-4-5-13-7-12(9)14-11/h2-3,6,13-14H,4-5,7H2,1H3
SMILES string
COc1ccc2[nH]c3CNCCc3c2c1
InChI key
QYMDEOQLJUUNOF-UHFFFAOYSA-N
assay
97%
form
powder or crystals
mp
219-222 °C (lit.)
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Gene Information
rat ... Htr2a(29595), Htr2c(25187)
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
R Pähkla et al.
Methods and findings in experimental and clinical pharmacology, 18(6), 359-366 (1996-07-01)
Pinoline (6-methoxy-1,2,3,4-tetrahydro-beta-carboline) has been found in similar concentrations to those of melatonin in various mammalian tissues. The present study investigates the subcellular distribution of in vivo administered [3H]-pinoline in mouse tissues using light and electron microscopic autoradiography. The antioxidative capacity
G Pless et al.
Journal of pineal research, 26(4), 236-246 (1999-05-26)
Oxygen consumption is a necessity for all aerobic organisms, but oxygen is also a toxic molecule that leads to the generation of free radicals. The brain consumes a high percentage of the oxygen inhaled (18.5%), and it contains large amounts
E Jane Cooper et al.
European journal of pharmacology, 482(1-3), 189-196 (2003-12-09)
It is well known that certain imidazoline compounds can stimulate insulin secretion and this has been attributed to the activation of imidazoline I(3) binding sites in the pancreatic beta-cell. Recently, it has been proposed that beta-carbolines may be endogenous ligands
A W Siu et al.
Journal of pineal research, 27(2), 122-128 (1999-09-25)
Oxidative damage to retinal cell membranes can lead to sight-threatening ocular diseases. Pineal indoleamines are naturally located and synthesized in the retina, and they possibly protect the retina from oxidative cell damage. In this study, we compared the efficacy of
J O Marcusson et al.
Molecular pharmacology, 30(2), 121-128 (1986-08-01)
Recently, a high affinity [3H]imipramine-binding site of protein nature that appeared to be related to the 5-hydroxytryptamine (5-HT, serotonin) uptake mechanism was demonstrated. This binding site was only part of desipramine-displaceable [3H]imipramine binding, which contained a significant amount of additional
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