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Merck
CN

290858

Sigma-Aldrich

壬基酚

technical grade, mixture of ring and chain isomers

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经验公式(希尔记法):
C15H24O
CAS号:
分子量:
220.35
Beilstein:
2047450
EC 号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

等级

technical grade

质量水平

折射率

n20/D 1.511 (lit.)

溶解性

water: slightly soluble 4.9 mg/L±0.4 mg/L

密度

0.937 g/mL at 25 °C (lit.)

SMILES字符串

CCCCCCCCCc1ccc(O)cc1

InChI

1S/C15H24O/c1-13(2)7-5-3-4-6-8-14-9-11-15(16)12-10-14/h9-13,16H,3-8H2,1-2H3

InChI key

JSFITYFUKSFPBZ-UHFFFAOYSA-N

基因信息

mouse ... Esr1(13982)
rat ... Ar(24208)

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一般描述

壬基酚是一种有毒的异生素化合物,属于内分泌干扰物,能够干扰许多生物的激素系统。已有报道称壬基酚可作为抗雄激素用于酵母检测系统。已研究报道了壬基酚的抗雄激素作用的分子机制

应用

  • Chlorination of Emerging Contaminants for Application in Potable Wastewater Reuse: Disinfection Byproduct Formation, Estrogen Activity, and Cytotoxicity.: Investigates the formation of disinfection byproducts, estrogen activity, and cytotoxicity during chlorination of nonylphenol in potable wastewater reuse applications, offering insights into water treatment safety protocols (Cochran et al., 2024).
  • Triple-Mode Sensor Coupled by Photoelectrochemical, Electrochromic, and Spectral Signals for Sensitive Visualized Detection of Nonylphenol.: Describes the development of a sensitive triple-mode sensor for detecting nonylphenol, integrating photoelectrochemical, electrochromic, and spectral signals, which could be instrumental in environmental monitoring and industrial process controls (Cao et al., 2023).

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 2 - Skin Corr. 1B

WGK

WGK 3

闪点(°F)

>235.4 °F

闪点(°C)

> 113 °C

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

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A Soares et al.
Environment international, 34(7), 1033-1049 (2008-02-20)
Nonylphenol is a toxic xenobiotic compound classified as an endocrine disrupter capable of interfering with the hormonal system of numerous organisms. It originates principally from the degradation of nonylphenol ethoxylates which are widely used as industrial surfactants. Nonylphenol ethoxylates reach
Hyun Ju Lee et al.
Toxicological sciences : an official journal of the Society of Toxicology, 75(1), 40-46 (2003-06-14)
By using a yeast detection system for androgenic and antiandrogenic effects of chemicals, we identified bisphenol A (BPA) and nonylphenol (NP) as antiandrogens. In this study, we report molecular mechanisms for the antiandrogenic action of BPA and NP. In the
C Uguz et al.
Andrologia, 47(8), 910-919 (2014-10-04)
The objective of this study was to determine the effects of nonylphenol (NP) on viability of ram and boar sperm in vitro. Ram or boar spermatozoa were exposed to 1, 10, 100, 250 and 500 μg NP ml(-1) for 1, 2, 3 or
Maurizio Forte et al.
Ecotoxicology and environmental safety, 180, 412-419 (2019-05-21)
Estrogens play a role in the patho-physiology of the prostate. In the present work we studied the effects of nonylphenol (NP), a xenoestrogen, on human adenocarcinoma prostate cells (LNCaP). In order to understand molecular and cellular involvement, we observed the
Tomasz Janicki et al.
Bioresource technology, 200, 223-229 (2015-10-23)
Nonylphenol (NP), 4-tert-octylphenol (4-t-OP) and 4-cumylphenol (4-CP) are pollutants that are known as endocrine disruptors mainly due to their estrogen-mimicking activity. These phenolic substances are used in a wide range of industrial and commercial applications. In the present study, biodegradation

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