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Merck
CN

290440

Sigma-Aldrich

3,5-二氟苯乙酸

99%

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About This Item

线性分子式:
F2C6H3CH2CO2H
分子量:
172.13
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

方案

99%

mp

68-70 °C (lit.)

SMILES字符串

OC(=O)Cc1cc(F)cc(F)c1

InChI

1S/C8H6F2O2/c9-6-1-5(3-8(11)12)2-7(10)4-6/h1-2,4H,3H2,(H,11,12)

InChI key

IGGNSAVLXJKCNH-UHFFFAOYSA-N

一般描述

3,5-Difluorophenylacetic acid is an important pharmaceutical intermediate.

应用

3,5-Difluorophenylacetic acid has been used in the synthesis of:
  • N-[N-(3,5-difluorophenylacetyl)-L-alanyl]-L-phenylglycine tert-butyl ester
  • N-acylalanine

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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分析证书(COA)

Lot/Batch Number

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访问文档库

Gilles Quéléver et al.
Organic & biomolecular chemistry, 3(13), 2450-2457 (2005-06-25)
Inhibition of gamma-secretase, one of the enzymes responsible for the cleavage of the amyloid precursor protein (APP) to produce pathogenic Abeta peptides, is an attractive approach for the treatment of Alzheimer's disease. We designed a gamma-secretase inhibitor bearing an ascorbic
Synthesis of dihalophenylacetic acids using aromatic nucleophilic substitution strategy.
Kowalczyk BA.
Synthesis, 1997(12), 1411-1414 (1997)
Synthesis of a tetrahydroimidazo [2', 1': 2, 3] thiazolo [5, 4-c] pyridine derivative with Met inhibitory activity.
Amat M, et al.
ARKIVOC (Gainesville, FL, United States), 3, 145-151 (2010)

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