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Merck
CN

290440

Sigma-Aldrich

3,5-二氟苯乙酸

99%

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线性分子式:
F2C6H3CH2CO2H
分子量:
172.13
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

检测方案

99%

mp

68-70 °C (lit.)

SMILES字符串

OC(=O)Cc1cc(F)cc(F)c1

InChI

1S/C8H6F2O2/c9-6-1-5(3-8(11)12)2-7(10)4-6/h1-2,4H,3H2,(H,11,12)

InChI key

IGGNSAVLXJKCNH-UHFFFAOYSA-N

一般描述

3,5-Difluorophenylacetic acid is an important pharmaceutical intermediate.

应用

3,5-Difluorophenylacetic acid has been used in the synthesis of:
  • N-[N-(3,5-difluorophenylacetyl)-L-alanyl]-L-phenylglycine tert-butyl ester
  • N-acylalanine

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Gilles Quéléver et al.
Organic & biomolecular chemistry, 3(13), 2450-2457 (2005-06-25)
Inhibition of gamma-secretase, one of the enzymes responsible for the cleavage of the amyloid precursor protein (APP) to produce pathogenic Abeta peptides, is an attractive approach for the treatment of Alzheimer's disease. We designed a gamma-secretase inhibitor bearing an ascorbic
Synthesis of a tetrahydroimidazo [2', 1': 2, 3] thiazolo [5, 4-c] pyridine derivative with Met inhibitory activity.
Amat M, et al.
ARKIVOC (Gainesville, FL, United States), 3, 145-151 (2010)
Synthesis of dihalophenylacetic acids using aromatic nucleophilic substitution strategy.
Kowalczyk BA.
Synthesis, 1997(12), 1411-1414 (1997)

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