product name
L-脯氨酸甲酯 盐酸盐, 98%
质量水平
检测方案
98%
形式
solid
旋光性
[α]20/D −31°, c = 0.5 in H2O
反应适用性
reaction type: solution phase peptide synthesis
mp
69-71 °C (lit.)
应用
peptide synthesis
SMILES字符串
Cl[H].[H][C@]1(CCCN1)C(=O)OC
InChI
1S/C6H11NO2.ClH/c1-9-6(8)5-3-2-4-7-5;/h5,7H,2-4H2,1H3;1H/t5-;/m0./s1
InChI key
HQEIPVHJHZTMDP-JEDNCBNOSA-N
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相关类别
应用
L-脯氨酸甲酯盐酸盐可用作：
- 肽合成的结构单元。
- 通过与芳基醛、乙酰乙酸甲酯和脲的缩合反应合成3,4-二氢嘧啶-2-(1H)-酮的催化剂。
- 制备脯氨酰脯氨酸的反应物。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Studies on the Biginelli reaction: a mild and selective route to 3, 4-dihydropyrimidin-2 (1H)-ones via enamine intermediates
Mabry J and Ganem B
Tetrahedron Letters, 47(1), 55-56 (2006)
An efficient green synthesis of proline-based cyclic dipeptides under water-mediated catalyst-free conditions
Thajudeen H, et al.
Tetrahedron Letters, 51(9), 1303-1305 (2010)
Synthesis of Prolylproline
Gaidukevich VA, et al.
Russ. J. Org. Chem., 55(7), 1005-1008 (2019)
Ernest Mordret et al.
Molecular cell, 75(3), 427-441 (2019-07-30)
The translation machinery and the genes it decodes co-evolved to achieve production throughput and accuracy. Nonetheless, translation errors are frequent, and they affect physiology and protein evolution. Mapping translation errors in proteomes and understanding their causes is hindered by lack
Emily M Christensen et al.
The Journal of biological chemistry, 295(52), 18316-18327 (2020-10-29)
Pyrroline-5-carboxylate reductase 1 (PYCR1) catalyzes the biosynthetic half-reaction of the proline cycle by reducing Δ1-pyrroline-5-carboxylate (P5C) to proline through the oxidation of NAD(P)H. Many cancers alter their proline metabolism by up-regulating the proline cycle and proline biosynthesis, and knockdowns of
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