287059
L-脯氨酰胺
98%, for peptide synthesis
别名:
(2S)-2-Carbamoylpyrrolidine
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关于此项目
经验公式（希尔记法）:
C5H10N2O
化学文摘社编号:
分子量:
114.15
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
231-397-0
MDL number:
Beilstein/REAXYS Number:
80807
产品名称
L-脯氨酰胺, 98%
InChI key
VLJNHYLEOZPXFW-BYPYZUCNSA-N
InChI
1S/C5H10N2O/c6-5(8)4-2-1-3-7-4/h4,7H,1-3H2,(H2,6,8)/t4-/m0/s1
SMILES string
NC(=O)[C@@H]1CCCN1
assay
98%
optical activity
[α]20/D −106°, c = 1 in ethanol
reaction suitability
reaction type: solution phase peptide synthesis
mp
95-97 °C (lit.)
application(s)
peptide synthesis
Quality Level
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Denis R St Laurent et al.
Bioorganic & medicinal chemistry letters, 22(19), 6063-6066 (2012-09-11)
In a previous disclosure,(1) we reported the dimerization of an iminothiazolidinone to form 1, a contributor to the observed inhibition of HCV genotype 1b replicon activity. The dimer was isolated via bioassay-guided fractionation experiments and shown to be a potent
Hidenobu Komeda et al.
European journal of biochemistry, 271(8), 1465-1475 (2004-04-07)
An amidase acting on (R,S)-piperazine-2-tert-butylcarboxamide was purified from Pseudomonas azotoformans IAM 1603 and characterized. The enzyme acted S-stereoselectively on (R,S)-piperazine-2-tert-butylcarboxamide to yield (S)-piperazine-2-carboxylic acid. N-terminal and internal amino acid sequences of the enzyme were determined. The gene encoding the S-stereoselective
Tor E Kristensen et al.
Organic letters, 11(14), 2968-2971 (2009-06-16)
A completely non-chromatographic and highly large-scale adaptable synthesis of acrylic polymer beads containing proline and prolineamides has been developed. Novel monomeric proline (meth)acrylates are prepared from hydroxyproline in only one step. Free-radical copolymerization then gives solid-supported proline organocatalysts directly in
Jozef Kozísek et al.
Acta crystallographica. Section A, Foundations of crystallography, 60(Pt 5), 510-516 (2004-10-13)
The experimental charge density of the Ni(II) complex of the Schiff base of (S)-N-(2-benzoylphenyl)-1-benzylprolinamide and glycine was derived from high-resolution single-crystal X-ray diffraction data (lambda = 0.5604 A) at low temperature (100 K) with synchrotron radiation at the beamline F1
Omar D Lopez et al.
Bioorganic & medicinal chemistry letters, 23(3), 779-784 (2013-01-01)
In a recent disclosure, we described the discovery of dimeric, prolinamide-based NS5A replication complex inhibitors exhibiting excellent potency towards an HCV genotype 1b replicon. That disclosure dealt with the SAR exploration of the peripheral region of our lead chemotype, and
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