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Merck
CN

284130

Sigma-Aldrich

补骨脂素

97%

别名:

6,7-富喃香豆素, 7H-呋喃 [3,2-g] 苯并吡喃-7-酮, 呋喃[3,2-g]香豆素, 呋喃并香豆素

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About This Item

经验公式(希尔记法):
C11H6O3
CAS号:
分子量:
186.16
Beilstein:
152784
EC 号:
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:

检测方案

97%

SMILES字符串

O=C1Oc2cc3occc3cc2C=C1

InChI

1S/C11H6O3/c12-11-2-1-7-5-8-3-4-13-9(8)6-10(7)14-11/h1-6H

InChI key

ZCCUUQDIBDJBTK-UHFFFAOYSA-N

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应用

用于研究核酸结构和功能的光化学试剂。

警告

Store in dark!

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral - Skin Sens. 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Karen S McGinnis et al.
Archives of dermatology, 139(6), 771-775 (2003-06-18)
Multimodality biological response-modifier therapy that includes photopheresis, interferon, and bexarotene is the standard of care in our institution for advanced cutaneous T-cell lymphoma with peripheral blood involvement. We added psoralen plus long-wave UV-A (PUVA) to this regimen in 5 patients
Takuya Furuhashi et al.
PloS one, 8(1), e54895-e54895 (2013-02-01)
Photo(chemo)therapy is widely used to treat psoriasis, the pathogenesis of which might be caused by an imbalance of Th17 cells/regulatory T cells (Treg). In the present study, we evaluated the effects of photo(chemo)therapy on the Th17/Treg balance and Treg function.
F P Gasparro et al.
Environmental and molecular mutagenesis, 31(2), 105-112 (1998-04-17)
Photochemotherapy employing 8-methoxypsoralen and ultraviolet radiation (PUVA) is widely used in the treatment of psoriasis. The photoactivation of psoralens in skin cells leads to DNA photoadduct formation which may be responsible for the efficacy of PUVA. Subsequent mutations may lead
miR-TRAP: a benchtop chemical biology strategy to identify microRNA targets.
Huricha Baigude et al.
Angewandte Chemie (International ed. in English), 51(24), 5880-5883 (2012-05-09)
Biochemical aspects of psoralen photochemotherapy.
A C Moor et al.
Clinics in dermatology, 14(4), 353-365 (1996-07-01)

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