283746
4-(氨甲基)苯甲酸
97%, for peptide synthesis
别名:
PAMBA
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关于此项目
线性分子式:
H2NCH2C6H4CO2H
化学文摘社编号:
分子量:
151.16
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352106
EC Number:
200-297-9
MDL number:
Beilstein/REAXYS Number:
1100606
产品名称
4-(氨甲基)苯甲酸, 97%
InChI key
QCTBMLYLENLHLA-UHFFFAOYSA-N
InChI
1S/C8H9NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,5,9H2,(H,10,11)
SMILES string
NCc1ccc(cc1)C(O)=O
assay
97%
form
powder
reaction suitability
reaction type: solution phase peptide synthesis
mp
≥300 °C (lit.)
application(s)
peptide synthesis
Quality Level
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Application
4-（氨基甲基）苯甲酸（PAMBA）可用于合成：
- 钴羧酸膦酸酯。
- Apoptozole（Az），具有促进突变囊性纤维化跨膜传导调节因子（CFTR）氯通道活性的膜运输的细胞效力。
- 环肽，由 L-谷氨酸和 3-氨基苯甲酸组成，可用作各种阳离子和阴离子的受体。
- 生物活性肽，具有有效的 GPR54（G 蛋白偶联受体）激动活性。
Other Notes
4-（氨基甲基）苯甲酸也是一种抗出血剂，用于治疗内出血。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Sandra Osburn et al.
Rapid communications in mass spectrometry : RCM, 21(21), 3409-3419 (2007-09-29)
Formation of [bn+17+cat]+ is a prominent collision-induced dissociation (CID) pathway for Li+- and Na+-cationized peptides. Dissociation of protonated and Ag+-cationized peptides instead favors formation of the rival bn+/[bn-1+cat]+ species. In this study the influence of a 4-aminomethylbenzoic acid (4AMBz) residue
A small molecule that binds to an ATPase domain of Hsc70 promotes membrane trafficking of mutant cystic fibrosis transmembrane conductance regulator.
Cho H J, et al.
Journal of the American Chemical Society, 133(50), 20267-20276 (2011)
Carlos F R A C Lima et al.
The journal of physical chemistry. A, 111(42), 10598-10603 (2007-10-05)
The standard (p0 = 0.1 MPa) molar enthalpies of combustion of six aminomethylbenzoic acids were measured at T = 298.15 K by static bomb calorimetry. With these values, the standard molar enthalpies of formation in the crystalline state were obtained.
G A Chalyĭ et al.
Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (1)(1), 62-65 (1993-01-01)
The influence of protease-inhibiting preparations on the development of humoral immune response in diseases involving the development of secondary immunodeficiency (experimentally induced acute pancreatitis and staphylococcal infection) has been studied. Five injections of contrycal and epsilon-aminocaproic acid (epsilon-ACA), starting from
M N Iakushenko et al.
Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (1)(1), 77-79 (1998-04-09)
The examination of 49 newborn infants revealed that at the early neonatal period the character of the microbial colonization of the intestine depended on the kind of perinatal pathology: in lesions of the central nervous system and conjugation jaundice the
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