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Merck
CN

283320

乳酸丁酯

98%

别名:

α-羟基丙酸丁酯, (±)-乳酸正丁酯, 2-羟基丙酸丁酯, 丁基α羟基丙酸酯, 丁基2- 羟基丙酸酯, 正丁基乳酸酯

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关于此项目

线性分子式:
CH3CH(OH)CO2(CH2)3CH3
化学文摘社编号:
分子量:
146.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
205-316-4
MDL number:
Assay:
98%
Form:
liquid
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InChI key

MRABAEUHTLLEML-UHFFFAOYSA-N

InChI

1S/C7H14O3/c1-3-4-5-10-7(9)6(2)8/h6,8H,3-5H2,1-2H3

SMILES string

CCCCOC(=O)C(C)O

vapor density

5.04 (vs air)

vapor pressure

0.4 mmHg ( 20 °C)

assay

98%

form

liquid

refractive index

n20/D 1.421 (lit.)

bp

185-187 °C (lit.)

mp

−28 °C (lit.)

density

0.984 g/mL at 25 °C (lit.)

functional group

ester, hydroxyl

Quality Level

Application

乳酸丁酯可用于:
  • 通过乳化扩散技术制备固体脂质纳米颗粒
  • 通过溶剂扩散技术从水稀释性微乳液合成灰黄霉素纳米颗粒
  • 在使用阴离子表面活性剂制备微乳液的过程中用作助表面活性剂

存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

156.2 °F - closed cup

flash_point_c

69 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Michele Trotta et al.
International journal of pharmaceutics, 257(1-2), 153-160 (2003-04-25)
A preparation method for nanoparticles based on the emulsification of a butyl lactate or benzyl alcohol solution of a solid lipid in an aqueous solution of different emulsifiers, followed by dilution of the emulsion with water, was used to prepare
Microemulsions with butyl lactate as cosurfactant.
<BIG>Comelles F and Pascual A. </BIG>
Journal of Dispersion Science and Technology, 18(2), 161-175 (1997)
Michele Trotta et al.
International journal of pharmaceutics, 254(2), 235-242 (2003-03-08)
Nanoparticles of griseofulvin, a model drug with poor solubility and low bioavailability, were prepared from water dilutable microemulsions by the solvent diffusion technique. Solvent-in-water microemulsion formulations containing water, butyl lactate, lecithin, taurodeoxycholate sodium salt (TDC) or dipotassium glycyrrhizinate (KG), 1,2-propanediol
Daniela Chirio et al.
International journal of molecular sciences, 19(12) (2018-12-06)
Chitosan is an excipient which has been studied thoroughly in research works thanks to its positive characteristics such as muco-adhesiveness and ability to open epithelial-tight-junctions. In this article, lipophilic stearoyl chitosan (ST-CS) was synthetized in order to anchor this polymer
Domenico Pirozzi et al.
Biotechnology progress, 22(2), 444-448 (2006-04-08)
The alpha-hydroxy esters are increasingly employed in cosmetic, food, and pharmaceutical formulations as they determine reduced skin-irritant effects in comparison with the respective acids, offering similar hygroscopic, emulsifying, and exfoliating properties. The enzymatic synthesis of lactate esters in nonaqueous systems

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