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Merck
CN

282227

洗必泰

≥99.5%

别名:

1,1′-己基双[5-(对氯苯基)双胍]

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关于此项目

线性分子式:
[-(CH2)3NHC(=NH)NHC(=NH)NHC6H4Cl]2
化学文摘社编号:
分子量:
505.45
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-238-7
Beilstein/REAXYS Number:
2826432
MDL number:
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产品名称

洗必泰, ≥99.5%

InChI key

GHXZTYHSJHQHIJ-UHFFFAOYSA-N

InChI

1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34)

SMILES string

Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1

assay

≥99.5%

form

powder

impurities

<1.0% water

mp

134-136 °C (lit.)

solubility

water: soluble 0.08% at 20 °C

functional group

amine
chloro

Quality Level

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Application

氯己定是口服防腐剂的“金标准”,已被用于优化外科缝线中基于脂肪酸的新型缓释氯己定涂层。。氯己定,一种抗菌剂,已被用于制备氯己定功能化的磷酸钙纳米粒子,其可用于口腔卫生和牙科治疗领域

General description

已对氯己定:羟丙基-β-环糊精包含物对牛牙本质体外平板的影响进行了研究

氯己定是一种阳离子表面活性剂,具有广谱抗微生物活性。它用作牙周治疗和手术刷洗中的消毒剂。

pictograms

CorrosionEnvironment

signalword

Danger

hcodes

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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分析证书(COA)

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Carolina Ferreira Franco et al.
Artificial organs, 27(5), 486-491 (2003-05-20)
The aim of this work was study the effect of the chlorhexidine : hydroxypropyl-beta-cyclodextrin (CLX : HP-beta-CD) inclusion compound (IC) on in vitro slabs of bovine dentine. The substantivity, antimicrobial activity, and morphological effect of this inclusion compound were evaluated.
Effect of a chlorhexidine mouthrinse on plaque, gingival inflammation and staining in gingivitis patients: a systematic review
Van Strydonck DA, et al.
Journal of Clinical Periodontology, 39, 1042-1055 (2012)
Chlorhexidine-loaded calcium phosphate nanoparticles for dental maintenance treatment: combination of mineralising and antibacterial effects.
Kovtun A, et al.
Royal Society of Chemistry Advances, 2(3), 870-875 (2012)
Matthias Maiwald et al.
PloS one, 7(9), e44277-e44277 (2012-09-18)
Skin antisepsis is a simple and effective measure to prevent infections. The efficacy of chlorhexidine is actively discussed in the literature on skin antisepsis. However, study outcomes due to chlorhexidine-alcohol combinations are often attributed to chlorhexidine alone. Thus, we sought
Carolyne Horner et al.
The Journal of antimicrobial chemotherapy, 67(11), 2547-2559 (2012-07-27)
Antiseptic agents are increasingly used for hand hygiene and skin decolonization as key tools for the prevention of healthcare-associated infections. Chlorhexidine, a divalent, cationic biguanide, has a broad spectrum of activity and is one of the most frequently used topical

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