281255
1,4-二羟基-2-萘甲酸
97%
别名:
1,4-二羟基-2-萘甲酸, 1,4-二羟基-2-萘甲酸盐
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关于此项目
线性分子式:
(HO)2C10H5CO2H
化学文摘社编号:
分子量:
204.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
250-674-7
MDL number:
Assay:
97%
InChI key
VOJUXHHACRXLTD-UHFFFAOYSA-N
InChI
1S/C11H8O4/c12-9-5-8(11(14)15)10(13)7-4-2-1-3-6(7)9/h1-5,12-13H,(H,14,15)
SMILES string
OC(=O)c1cc(O)c2ccccc2c1O
assay
97%
mp
220 °C (dec.) (lit.)
functional group
carboxylic acid
Quality Level
General description
目前确知来自费氏丙酸杆菌的1,4--二羟基-2-萘甲酸可促进双歧杆菌增殖。这种产品在牛皮癣治疗中具有潜在的治疗应用。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Biosynthesis of vitamin K (menaquinone) in bacteria.
R Bentley et al.
Microbiological reviews, 46(3), 241-280 (1982-09-01)
Pallavi P Murugkar et al.
Journal of oral microbiology, 12(1), 1814666-1814666 (2020-11-20)
The vast majority of bacteria on earth have not yet been cultivated. There are many bacterial phyla with no cultivated examples including most members of the Candidate Phylum Radiation with the exception of human oral isolates from the phylum Saccharibacteria.
Site of prenylation reaction in synthesis of phylloquinone (vitamin K1) by spinach chloroplasts.
G Schultz et al.
European journal of biochemistry, 117(2), 329-332 (1981-07-01)
Kumiko Nagata et al.
Helicobacter, 15(5), 422-429 (2010-11-19)
Triple therapy with amoxicillin, clarithromycin, and a proton-pump inhibitor is a common therapeutic strategy for the eradication of Helicobacter pylori (H. pylori). However, frequent appearance of clarithromycin-resistant strains is a therapeutic challenge. While various quinones are known to specifically inhibit
M Matsubara et al.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 21(8), 1437-1447 (2009-10-09)
The main component of the metabolic by-products of fermentation by Propionibacterium freudenreichii ET-3 is 1,4-dihydroxy-2-naphthoic acid (DHNA), which has a naphthoquinone skeleton, as in vitamin K2. This study showed that DHNA improved bone mass reduction with osteoporosis model mice caused
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