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276170

Sigma-Aldrich

N,N-二甲基苯甲酰胺

99%

别名:

DMBZ

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About This Item

线性分子式:
C6H5CON(CH3)2
CAS号:
611-74-5
分子量:
149.19
EC 号:
210-279-2
MDL编号:
MFCD00008320
UNSPSC代码:
12352100
PubChem化学物质编号:
24856689
NACRES:
NA.22

质量水平

200

方案

99%

表单

solid

沸点

132-133 °C/15 mmHg (lit.)

mp

43-45 °C (lit.)

官能团

amide
phenyl

SMILES字符串

CN(C)C(=O)c1ccccc1

InChI

1S/C9H11NO/c1-10(2)9(11)8-6-4-3-5-7-8/h3-7H,1-2H3

InChI key

IMNDHOCGZLYMRO-UHFFFAOYSA-N

相关类别

一般描述

N,N -二甲基苯甲酰胺是一种亲水剂，它对水溶性低的药物的增溶能力已被研究过 。它与 PhLnI 的配合物 (Ln-Eu，Sm，Yb) 反应生成二苯甲酮，收率良好 。在 N,N -二甲基苯甲酰胺上，使用 [IrH2(Me2CO)2(PPh3)2]BF4 作为催化剂，氘气作为同位素源进行氘交换标记 。

应用

用于仲醇的脱氧反应的试剂。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

235.4 °F - closed cup

闪点(°C)

113 °C - closed cup

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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分析证书(COA)

Lot/Batch Number
02124BI
03804AV
03807HU
17114BI
11816AN

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Deuterium exchange labelling of substituted aromatics using [IrH2 (Me2CO) 2 (PPh3)2] BF4.
Heys JR, et al.
Journal of Labelled Compounds & Radiopharmaceuticals, 33(5), 431-438 (1993)
Reactions of ethyl-and phenyllanthanide s complexes with n, n-dimethylbenzamide and benzaldehyde.
Yokoo K, et al.
Polyhedron, 2(10), 1101-1102 (1983)
Ji Young Kim et al.
Journal of controlled release : official journal of the Controlled Release Society, 152(1), 13-20 (2011-03-01)
Polymer micelles have been used widely for delivery of poorly water-soluble drugs. Such drug delivery, however, has been based primarily on hydrophobic interactions. For better drug loading and improved stability, hydrotropic polymer micelles were used. To develop a versatile polymer
L R Hall et al.
The Journal of biological chemistry, 265(21), 12349-12355 (1990-07-25)
Liver microsomal cytochrome P-450 readily N-dealkylates N,N-dimethylamides. N-Methyl-N-hydroxymethyl amides were isolated as intermediates and characterized by gas chromatography-mass spectrometry as their trimethylsilyl ethers. Intramolecular kinetic deuterium isotope effects measured for the enzymic N-demethylation of a series of 12 aromatic and
Ji Young Kim et al.
Journal of pharmaceutical sciences, 99(9), 3953-3965 (2010-07-08)
The solubilizing ability of two aromatic hydrotropes, N,N-diethylnicotinamide (DENA) and N,N-dimethylbenzamide (DMBA), was investigated using a set of 13 poorly soluble, structurally diverse drugs. The number of aromatic rings in the solute molecule has a very strong effect on the
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