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Merck
CN

274666

Sigma-Aldrich

百里香醌

≥98%

别名:

2-异丙基-5-甲基-1,4-苯醌

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About This Item

经验公式(希尔记法):
C10H12O2
CAS号:
分子量:
164.20
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47

质量水平

方案

≥98%

表单

solid

技术

titration: suitable

颜色

yellow

沸点

230-232 °C (lit.)

mp

45-47 °C (lit.)

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

CC(C)C1=CC(=O)C(C)=CC1=O

InChI

1S/C10H12O2/c1-6(2)8-5-9(11)7(3)4-10(8)12/h4-6H,1-3H3

InChI key

KEQHJBNSCLWCAE-UHFFFAOYSA-N

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一般描述

百里香醌 (TQ) 又称 2-异丙基-5-甲基-1,4-苯醌,存在于一种三斜晶型。为黑种子挥发油的生物活性成分。TQ 在体外体内均表现出抗炎、抗氧化和抗肿瘤作用。

应用

百里醌已用于抑制大肠杆菌ATP合酶和细胞生长。还用作药物治疗下肢坐骨神经和股肌的缺血再灌注损伤。
百里醌在临床前研究中可用作神经保护和抗惊厥药。

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

219.2 °F - closed cup

闪点(°C)

104 °C - closed cup

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Thymoquinone: A promising anti-cancer drug from natural sources
Gali-Muhtasib H
The International Journal of Biochemistry & Cell Biology, 38, 1249-1253 (2006)
Sanjar Alam et al.
International journal of nanomedicine, 7, 5705-5718 (2012-11-28)
Chitosan (CS) nanoparticles of thymoquinone (TQ) were prepared by the ionic gelation method and are characterized on the basis of surface morphology, in vitro or ex vivo release, dynamic light scattering, and X-ray diffractometry (XRD) studies. Dynamic laser light scattering
Hala Gali-Muhtasib et al.
The international journal of biochemistry & cell biology, 38(8), 1249-1253 (2005-11-30)
There has been growing interest in naturally occurring compounds with anti-cancer potential. Black seed is one of the most extensively studied plants. This annual herb grows in countries bordering the Mediterranean Sea and India. Thymoquinone (TQ) is the bioactive constituent
Thymoquinone Inhibits Escherichia coli ATP Synthase and Cell Growth
Ahmad Z
PLoS ONE, 10 (2015)
Chern Chiuh Woo et al.
Biochemical pharmacology, 83(4), 443-451 (2011-10-19)
Thymoquinone is an active ingredient isolated from Nigella sativa and has been investigated for its anti-oxidant, anti-inflammatory and anticancer activities in both in vitro and in vivo models since its first extraction in 1960s. Its anti-oxidant/anti-inflammatory effect has been reported

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