274623
戴斯-马丁氧化剂
97%
别名:
1,1,1-三(乙酰氧基)-1,1-二氢-1,2-苯碘酰-3-(1H)-酮
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选择尺寸
关于此项目
经验公式（希尔记法）:
C13H13IO8
化学文摘社编号:
分子量:
424.14
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
Assay:
97%
InChI
1S/C13H13IO8/c1-8(15)19-14(20-9(2)16,21-10(3)17)12-7-5-4-6-11(12)13(18)22-14/h4-7H,1-3H3
SMILES string
CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc12
InChI key
NKLCNNUWBJBICK-UHFFFAOYSA-N
assay
97%
reaction suitability
reagent type: oxidant
mp
130-133 °C (lit.)
functional group
iodo
storage temp.
−20°C
Quality Level
General description
Dess-Martin氧化剂(DMP)是一种高价碘化合物，广泛用作伯/仲醇氧化为醛/酮的温和试剂；酰胺氧化成酰亚胺以及胺脱氢成腈，二硫化物脱氢为砜。也用于将烯烃选择性氧化为环氧化物，作为生产三元环醚的有用反应。DMP还用于将1,2-二醇氧化裂解为醛或酮。可用于合成内酯。
Application
Dess–Martin高碘烷可用作以下反应的氧化剂：
- 一级和二级醇氧化为醛和酮的反应。
- 以相应的N-保护β-氨基醇合成N-保护α-氨基醛。
- 合成乙炔基氧化醛探针（AlkMGO）。
用于将羟基二氢卟酚氧化为二氢卟酚-α-二酮和四酮。
Features and Benefits
使用 DMP 作为氧化试剂的好处：
- 较温和的反应条件（室温、中性 pH）
- 更短的反应时间和更高的产率
- 高化学选择性
- 敏感官能团的耐受性和较长的保质期
- 简化的检查
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Self-react. C - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
supp_hazards
存储类别
5.2 - Organic peroxides and self-reacting hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Andrew GM,et al.
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商品
Dess-Martin Periodinane enables mild oxidation of alcohols to aldehydes and ketones suitable for synthesizing complex intermediates.
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