推荐产品
质量水平
检测方案
98%
形式
solid
mp
110-111 °C (lit.)
SMILES字符串
COC(=O)c1ccc(N)cc1
InChI
1S/C8H9NO2/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5H,9H2,1H3
InChI key
LZXXNPOYQCLXRS-UHFFFAOYSA-N
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一般描述
研究了过氧化氢对 4-氨基苯甲酸甲酯的催化氧化。
应用
4-氨基苯甲酸甲酯用于通过质子酸催化的杂 Diels-Alder 与 N-Cbz 2-吡咯啉的偶联反应合成胍生物碱、(±)-马二碱和(±)-马来酸。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Chemical & pharmaceutical bulletin, 55(11), 1647-1648 (2007-11-06)
Chemical investigation of the wood-decayed fungus Xylaria sp. BCC 9653 has led to the isolation of a new methyl aminobenzoate (1) together with eleven known compounds. The structures were established by analysis of spectroscopic data. Cytochalasin D (2), one of
Journal of pharmaceutical sciences, 84(6), 673-676 (1995-06-01)
The major influence on the rate of drug transfer out of its vehicle and into the skin is the thermodynamic activity of the drug within its formulation. This study addresses certain thermodynamic dependencies of topical delivery in a model system.
The Journal of pharmacy and pharmacology, 72(3), 356-363 (2019-12-13)
Grapefruit (Citrus paradisi) juice enhances the oral bioavailability of drugs that are metabolized by intestinal cytochrome P450 3A4 (CYP3A4). Patients are advised to avoid drinking grapefruit juice to prevent this drug-grapefruit juice interaction. The aim of this study was to
The Journal of organic chemistry, 70(6), 2350-2352 (2005-03-12)
[reaction: see text] Reaction conditions are described for the oxidation of anilines furnishing nitrosoarenes and the synthesis of unsymmetrically substituted azobenzenes. In a comparative study, the catalytic oxidation of methyl 4-aminobenzoate by hydrogen peroxide was investigated, and SeO(2) proved to
Bioorganic & medicinal chemistry letters, 21(24), 7363-7366 (2011-11-02)
As the primary step for 'drug repositioning', we evaluated the effect of 2000 drugs and drug candidates on the commitment of bi-potential mesenchymal precursor C2C12 cells into osteoblasts in the presence of bone morphogenetic protein (BMP)-2 and found that butamben
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