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Merck
CN

269913

Supelco

3-(三甲基甲硅烷基)丙酸-d4 钠盐

98 atom % D

别名:

3-(三甲基甲硅烷基)丙酸钠-2,2,3,3-d4, 3-三甲基硅烷基丙酸-2,2,3,3-d4 酸 钠盐, TSP-d4

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About This Item

线性分子式:
(CH3)3SiCD2CD2CO2Na
CAS号:
分子量:
172.27
Beilstein:
4046239
EC 号:
MDL编号:
UNSPSC代码:
12000000
PubChem化学物质编号:
NACRES:
NA.22

同位素纯度

98 atom % D

质量水平

检测方案

≥98.0% (NMR)

杂质

≤0.5% water (Karl Fischer)

pH值(酸碱度)

7.0-9.0 (1% in solution)

质量偏移

M+4

SMILES字符串

[Na+].[2H]C([2H])(C([O-])=O)C([2H])([2H])[Si](C)(C)C

InChI

1S/C6H14O2Si.Na/c1-9(2,3)5-4-6(7)8;/h4-5H2,1-3H3,(H,7,8);/q;+1/p-1/i4D2,5D2;

InChI key

OIIWPAYIXDCDNL-HGFPCDIYSA-M

应用


  • Rapid separation and quantitation of curcuminoids combining pseudo two-dimensional liquid flash chromatography and NMR spectroscopy: This research demonstrates the application of 3-(Trimethylsilyl)propionic-2,2,3,3-d₄ acid sodium salt in the field of NMR spectroscopy, particularly emphasizing its role as an internal standard in the quantification of curcuminoids. The study showcases a novel method that combines pseudo two-dimensional liquid flash chromatography with NMR spectroscopy, providing a faster, more accurate analytical approach. This method significantly enhances the efficiency and reliability of chemical analysis in pharmaceutical and biomedical research, making it a valuable technique for analytical chemists in academia (Jayaprakasha et al., 2013).


WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

美国出口管控1C298产品

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The Journal of toxicological sciences, 44(1), 57-71 (2019-01-11)
Cisplatin (CP) is an anti-cancer drug used for treatment of solid tumors, but the major adverse effect is drug-induced nephrotoxicity. The current study aimed to determine biomarkers that might predict nephrotoxicity induced by CP using serum or urinary proton nuclear
Qiongju Cao et al.
Food & function, 11(4), 3095-3104 (2020-03-21)
Soups show diverse health functions, which could be linked to their original nutrient profiles and metabolites derived from digestion. NMR spectroscopy is a robust and rapid method that unveils or identifies the chemical composition of food or food-derived metabolites. In
Aline L Baptista et al.
JBMR plus, 4(7), e10372-e10372 (2020-07-16)
Bone biopsy is still the gold standard to assess bone turnover (T), mineralization (M), and volume (V) in CKD patients, and serum biomarkers are not able to replace histomorphometry. Recently, metabolomics has emerged as a new technique that could allow
Efthymia Papaevangelou et al.
International journal of cancer, 143(4), 992-1002 (2018-03-24)
Overexpression of fatty acid synthase (FASN), a key regulator of the de novo synthesis of fatty acids, has been demonstrated in a variety of cancers and is associated with poor prognosis and increased multidrug resistance. Inhibition of FASN with the
Ioanna Dagla et al.
Talanta, 178, 246-257 (2017-11-16)
Metabolic syndrome (MetS) represents a group of abnormalities that enhances the risk for cardiovascular disease, diabetes and stroke. The Mediterranean diet seems to be an important dietary pattern, which reduces the incidence of MetS. Hydroxytyrosol (HT) - a simple phenol

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