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质量水平
方案
≥97%
表单
crystals
折射率
n20/D 1.5775 (lit.)
沸点
139-140 °C/14 mmHg (lit.)
mp
26-29 °C (lit.)
官能团
sulfoxide
储存温度
2-8°C
SMILES字符串
CS(=O)c1ccccc1
InChI
1S/C7H8OS/c1-9(8)7-5-3-2-4-6-7/h2-6H,1H3
InChI key
JXTGICXCHWMCPM-UHFFFAOYSA-N
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一般描述
(R)- 甲基苯基亚砜是一种重要的药物中间体。
应用
甲基苯基亚砜可用于合成:
- 同位素标记的1,3-二噻烷,一种有用的标记合成子
- 奈非那韦,强效HIV蛋白酶抑制剂
- 亚砜亚胺和溶剂-水分配的研究中
警示用语:
Danger
危险声明
危险分类
Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
186.8 °F - closed cup
闪点(°C)
86 °C - closed cup
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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An asymmetric synthesis of nelfinavir is described starting from acrolein and (S)-methyl phenyl sulfoxide. The key features include (a) stereoselective preparation of a beta-protected amino-gamma,delta-unsaturated sulfoxide by the reaction of an alpha-sulfinyl carbanion with an unsaturated t-butyl sulfinylimine, (b) stereoselective
Journal of pharmaceutical sciences, 83(8), 1085-1100 (1994-08-01)
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Endocytosis is critical for many cellular functions. We show that endocytosis of the common gammac cytokine receptor is clathrin independent by using a dominant-negative mutant of Eps15 or RNA interference to knock down clathrin heavy chain. This pathway is synaptojanin
Journal of the American Chemical Society, 127(33), 11736-11744 (2005-08-18)
The induction of a cholesteric phase by doping an achiral nematic liquid crystal with an enantiopure solute is a phenomenon that, as in all general supramolecular phenomena of chiral amplification, depends in a subtle way on intermolecular interactions. The micrometric
Chromatograms
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