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Merck
CN

261696

Sigma-Aldrich

甲基苯基亚砜

≥97%

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About This Item

线性分子式:
CH3SOC6H5
CAS号:
分子量:
140.20
Beilstein:
1904976
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

≥97%

表单

crystals

折射率

n20/D 1.5775 (lit.)

沸点

139-140 °C/14 mmHg (lit.)

mp

26-29 °C (lit.)

官能团

sulfoxide

储存温度

2-8°C

SMILES字符串

CS(=O)c1ccccc1

InChI

1S/C7H8OS/c1-9(8)7-5-3-2-4-6-7/h2-6H,1H3

InChI key

JXTGICXCHWMCPM-UHFFFAOYSA-N

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一般描述

(R)- 甲基苯基亚砜是一种重要的药物中间体

应用

甲基苯基亚砜可用于合成:
  • 同位素标记的1,3-二噻烷,一种有用的标记合成子
  • 奈非那韦,强效HIV蛋白酶抑制剂
  • 亚砜亚胺和溶剂-水分配的研究中

象形图

CorrosionExclamation mark

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

186.8 °F - closed cup

闪点(°C)

86 °C - closed cup

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Aldrichimica Acta, 18, 3-3 (1985)
Sadagopan Raghavan et al.
The Journal of organic chemistry, 75(2), 498-501 (2009-12-17)
An asymmetric synthesis of nelfinavir is described starting from acrolein and (S)-methyl phenyl sulfoxide. The key features include (a) stereoselective preparation of a beta-protected amino-gamma,delta-unsaturated sulfoxide by the reaction of an alpha-sulfinyl carbanion with an unsaturated t-butyl sulfinylimine, (b) stereoselective
M H Abraham et al.
Journal of pharmaceutical sciences, 83(8), 1085-1100 (1994-08-01)
A general linear solvation energy equation has been used to analyze published partition coefficients in the systems water-octanol (613 solutes), water-hexadecane (370 solutes), water-alkane (200 solutes), and water-cyclohexane (170 solutes). The descriptors used in the equation are R2, an excess
Nathalie Sauvonnet et al.
The Journal of cell biology, 168(1), 155-163 (2004-12-30)
Endocytosis is critical for many cellular functions. We show that endocytosis of the common gammac cytokine receptor is clathrin independent by using a dominant-negative mutant of Eps15 or RNA interference to knock down clathrin heavy chain. This pathway is synaptojanin
Giorgio Celebre et al.
Journal of the American Chemical Society, 127(33), 11736-11744 (2005-08-18)
The induction of a cholesteric phase by doping an achiral nematic liquid crystal with an enantiopure solute is a phenomenon that, as in all general supramolecular phenomena of chiral amplification, depends in a subtle way on intermolecular interactions. The micrometric

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