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Merck
CN

261394

1,1-二甲基脲

99%

别名:

N,N-二甲基脲

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关于此项目

线性分子式:
(CH3)2NCONH2
化学文摘社编号:
分子量:
88.11
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
209-957-0
MDL number:
Assay:
99%
Form:
solid
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InChI key

YBBLOADPFWKNGS-UHFFFAOYSA-N

InChI

1S/C3H8N2O/c1-5(2)3(4)6/h1-2H3,(H2,4,6)

SMILES string

CN(C)C(N)=O

assay

99%

form

solid

mp

178-183 °C (lit.)

solubility

water: soluble 5%, clear, colorless

functional group

amine

Quality Level

Gene Information

human ... EPHX2(2053)
mouse ... Ephx2(13850)

General description

Nonlinear optical properties of 1,1-dimethylurea (N,N′ dimethylurea), have been evaluated through second-harmonic generation.

Application

1,1-Dimethylurea (N,N-dimethylurea) has been used in the Dowex-50W ion exchange resin-promoted synthesis of N,N′-disubstituted-4-aryl-3,4-dihydropyrimidinones.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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S Sandler et al.
Diabetologia, 23(4), 374-378 (1982-10-01)
The protective effect on streptozotocin-induced diabetes of dimethyl urea, a hydroxyl radical scavenger, has been evaluated in vivo and in vitro. Pretreatment with dimethyl urea before a single diabetogenic dose of streptozotocin partially protected NMRI mice from hyperglycaemia, whereas the
G L Wilson et al.
Diabetologia, 27(6), 587-591 (1984-12-01)
In studies to evaluate possible inhibitors of the B-cell toxin, streptozotocin, the superoxide scavenger, superoxide dismutase, did not prevent or reduce the toxic effects of streptozotocin as determined by loss of insulin secretion from rat pancreatic B cells in monolayer
Nonlinear optical properties of N, N' dimethylurea.
Halbout JM, et al.
Applied Physics Letters, 37(10), 864-866 (2008)
S Sandler et al.
Acta pharmacologica et toxicologica, 53(5), 392-400 (1983-11-01)
The possible protective effects in vitro of the hydroxyl radical scavenger dimethyl urea (6 mg/ml) and the poly(ADP-ribose)synthetase inhibitors theophylline (5 mM) and nicotinamide (0.75 mg/ml) against streptozotocin (SZ) induced deterioration of islet metabolism were investigated using isolated mouse pancreatic
W J Caspary et al.
Mutation research, 174(4), 285-293 (1986-08-01)
Methylisocyanate (MIC) induced mutagenic responses in the absence of exogenous activation in the mouse lymphoma cell forward mutation assay at concentrations as low as 8-24 microM. MIC produced predominantly small mutant colonies, suggesting the possibility of clastogenic activity. The intermediate

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