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Merck
CN

259187

Sigma-Aldrich

海克替啶,立体异构体混合物

别名:

5-氨基-1,3-双(2-乙己基)六氢-5-甲基嘧啶, NSC 17764

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About This Item

经验公式(希尔记法):
C21H45N3
CAS号:
分子量:
339.60
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

表单

liquid

折射率

n20/D 1.4649 (lit.)

沸点

160 °C/0.4 mmHg (lit.)

溶解性

acetone: soluble(lit.)
benzene: soluble(lit.)
chloroform: soluble(lit.)
ethanol: soluble(lit.)
hexane: soluble(lit.)
methanol: soluble(lit.)
petroleum ether: soluble(lit.)
water: insoluble(lit.)

密度

0.889 g/mL at 25 °C (lit.)

SMILES字符串

CCCCC(CC)CN1CN(CC(CC)CCCC)CC(C)(N)C1

InChI

1S/C21H45N3/c1-6-10-12-19(8-3)14-23-16-21(5,22)17-24(18-23)15-20(9-4)13-11-7-2/h19-20H,6-18,22H2,1-5H3

InChI key

DTOUUUZOYKYHEP-UHFFFAOYSA-N

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一般描述

已研究海克替啶嗽口水削弱龈上菌斑和牙龈炎的有效性

应用

参与研究:
  • 鉴定(identify)阿司匹林的纯液体盐形式
  • 作为基于烷基的选择性置换剂候选,用于离子交换色谱法蛋白纯化
  • 体内应用模型,用于试验非复制结核分枝杆菌抗性药物
  • 将能量代谢从线粒体呼吸转变为糖酵解的药物的营养敏化筛选
  • 血管形成抑制
  • 抗疟药物筛选

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

158.0 °F - closed cup

闪点(°C)

70 °C - closed cup

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M Martin et al.
Der Anaesthesist, 61(1), 25-29 (2012-01-26)
A total of three intensive care units (ICU) at a German university hospital were involved in an outbreak of Burkholderia cepacia complex (Bcc). Patients with microbiological detection of Bcc were evaluated. Products used for mouth hygiene were microbiologically tested. The
N L Kunel'skaia et al.
Vestnik otorinolaringologii, (2)(2), 62-66 (2008-05-06)
A pilot trial of efficacy of the drugs lisobact and stomatidin in local treatment of acute pharyngitis and combined therapy of tonsillitis and paratonsillar abscess included 82 patients with tonsillitis (n=30), paratonsillar abscess (n=30) and acute pharyngitis (n=22) aged 15-72
Claus-Peter Ernst et al.
Quintessence international (Berlin, Germany : 1985), 36(8), 641-652 (2005-09-16)
The aim of this clinical, controlled double-blind trial was to evaluate the effectiveness and side effects of two different mouthrinses. Ninety subjects with gingivitis (or slight periodontitis) were randomly allocated to three groups: group 1, Chlorhexamed (0.1% chlorhexidine); group 2
A Jouyban et al.
Die Pharmazie, 57(4), 248-249 (2002-05-10)
A non-aqueous capillary electrophoresis method has been proposed to analyse hexetidine and its degradation products in a commercial liquid pharmaceutical formulation. The separation was achieved using a 37 cm fused silica capillary with a 75 microns internal diameter, an electrolyte
P A Jolivot et al.
Pathologie-biologie, 60(6), 362-368 (2012-03-01)
Establishment of an effective prophylaxis against oral candidiasis by local treatment is essential for immunocompromised patients. The aim of the study is to assess effectiveness and stability of antifungal suspensions for mouthrinses. The assessed suspensions are compounded by one solvent

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