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Merck
CN

259187

Sigma-Aldrich

海克替啶,立体异构体混合物

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别名:
5-氨基-1,3-双(2-乙己基)六氢-5-甲基嘧啶, NSC 17764
经验公式(希尔记法):
C21H45N3
CAS号:
分子量:
339.60
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

形式

liquid

折射率

n20/D 1.4649 (lit.)

bp

160 °C/0.4 mmHg (lit.)

溶解性

acetone: soluble(lit.)
benzene: soluble(lit.)
chloroform: soluble(lit.)
ethanol: soluble(lit.)
hexane: soluble(lit.)
methanol: soluble(lit.)
petroleum ether: soluble(lit.)
water: insoluble(lit.)

密度

0.889 g/mL at 25 °C (lit.)

SMILES字符串

CCCCC(CC)CN1CN(CC(CC)CCCC)CC(C)(N)C1

InChI

1S/C21H45N3/c1-6-10-12-19(8-3)14-23-16-21(5,22)17-24(18-23)15-20(9-4)13-11-7-2/h19-20H,6-18,22H2,1-5H3

InChI key

DTOUUUZOYKYHEP-UHFFFAOYSA-N

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一般描述

已研究海克替啶嗽口水削弱龈上菌斑和牙龈炎的有效性

应用

参与研究:
  • 鉴定(identify)阿司匹林的纯液体盐形式
  • 作为基于烷基的选择性置换剂候选,用于离子交换色谱法蛋白纯化
  • 体内应用模型,用于试验非复制结核分枝杆菌抗性药物
  • 将能量代谢从线粒体呼吸转变为糖酵解的药物的营养敏化筛选
  • 血管形成抑制
  • 抗疟药物筛选

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

158.0 °F

闪点(°C)

70 °C

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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G R Linke et al.
Endoscopy, 44(7), 684-689 (2012-04-25)
Animal data and limited clinical evidence suggest a low incidence of infection following transvaginal natural orifice transluminal endoscopic surgery (NOTES). However, a systematic microbiological evaluation has not yet been carried out. The aim of this prospective cohort study was to
P A Versteeg et al.
International journal of dental hygiene, 8(4), 269-275 (2010-10-22)
To test the plaque inhibitory effect of an experimental 0.07% cetylpyridinium chloride (CPC) mouthrinse in a 3-day plaque accumulation model in a cross-over design. A total of 30 subjects (non-dental students), ≥18 years of age, were randomly assigned to use
S Shapiro et al.
Caries research, 36(2), 93-100 (2002-05-31)
The ability of commercial mouthrinses to reduce total viable counts of mixed microbial populations was examined using a previously developed in vitro model of supragingival plaque. Exploratory experiments aimed at fine-tuning the model indicated that optimal correspondence between in vitro
H Pontefract et al.
Journal of clinical periodontology, 28(4), 319-324 (2001-04-21)
There are both anecdotal clinical and laboratory experimental data suggesting that low pH mouthrinses cause dental erosion. This evidence is particularly relevant to acidified sodium chlorite (ASC) formulations since they have plaque inhibitory properties comparable to chlorhexidine but without the
G Giuliana et al.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 87(1), 44-49 (1999-02-02)
Antimicrobial mouthrinses may represent a valid alternative to topical antifungal agents. However, the action of antimicrobials could be affected by the different ingredients incorporated into mouthrinse products. The purpose of the present study was to investigate the in vitro antifungal

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