所有图片(1)
别名:
8-Bromocaprylic acid
线性分子式:
Br(CH2)7CO2H
CAS号:
分子量:
223.11
Beilstein:
1756103
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.22
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质量水平
检测方案
97%
反应适用性
reagent type: cross-linking reagent
bp
147-150 °C/2 mmHg (lit.)
mp
35-37 °C (lit.)
官能团
bromo
carboxylic acid
SMILES字符串
OC(CCCCCCCBr)=O
InChI
1S/C8H15BrO2/c9-7-5-3-1-2-4-6-8(10)11/h1-7H2,(H,10,11)
InChI key
BKJFDZSBZWHRNH-UHFFFAOYSA-N
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一般描述
8-Bromooctanoic acid, also known as 8-bromocaprylic acid, is a cross-linking reagent. It can undergo hydrolysis to form 8-hydroxyoctanoic acid.
应用
8-Bromooctanoic acid can be used as a crosslinking reagent to:
- prepare 8-mercaptooctanoic acid in the biosynthesis of lipoic acid
- attach triple helix-forming oligonucleotides (TFOs) to inhibitors in their synthesis
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Skin Corr. 1B
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Synthesis of heteroatom-substituted analogues of stearic acid.
RA Pascal
Journal of Lipid Research, 27, 221-224 (1986)
Biosynthesis of lipoic acid: characterization of the lipoic acid auxotrophs Escherichia coli W1485-lip2 and JRG33-lip9
MA Hayden
Biochemistry, 32, 3778-3782 (1993)
Triple helix-forming oligonucleotides conjugated to new inhibitors of topoisomerase II: synthesis and binding properties
M Duca
Bioconjugate Chemistry, 16, 873-884 (2005)
Soumen Das et al.
Journal of labelled compounds & radiopharmaceuticals, 61(14), 1048-1057 (2018-09-02)
123 I-Iodophenylpentadecanoic acid (IPPA) is a metabolic agent used in nuclear medicine for diagnosis of myocardial defects. Efforts are underway worldwide to develop a 99m Tc substitute of the above radiopharmaceutical for the aforementioned application. Herein, we report synthesis and
Beibei Hou et al.
Materials science & engineering. C, Materials for biological applications, 74, 94-102 (2017-03-04)
How to encapsulate and transport the payload of multiple therapeutic compounds avoiding premature leakage, and simultaneously co-release them rapidly at specific lesions still remains the major concern in clinic. Herein, we designed the UCN@mSiO
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