253596
16-羟硬脂酸，自由基
别名:
2-(14-羧十四烷基)-2-乙基-4,4-二甲基-3-恶唑烷基氧自由基
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关于此项目
经验公式（希尔记法）:
C22H42NO4
化学文摘社编号:
分子量:
384.57
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
Form:
solid
InChI
1S/C22H42NO4/c1-4-22(23(26)21(2,3)19-27-22)18-16-14-12-10-8-6-5-7-9-11-13-15-17-20(24)25/h4-19H2,1-3H3,(H,24,25)
SMILES string
CCC1(CCCCCCCCCCCCCCC(O)=O)OCC(C)(C)N1[O]
InChI key
RPAZYIOIDZRJOO-UHFFFAOYSA-N
form
solid
mp
47-55 °C (lit.)
functional group
carboxylic acid, ether
storage temp.
2-8°C
Quality Level
Application
用于膜流动性研究的自旋标记物。
用于膜研究，包括：
- 利用1H动态核极化，研究脂质双层内部水的动力学和状态
- 脂肪酸的分布
- 氮氧化物的横向弛豫，用于PELDOR光谱学分析
- 不同脂质成分对抗去垢剂膜的影响
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
N Rapoport et al.
Archives of biochemistry and biophysics, 384(1), 100-108 (2001-01-09)
To assess the effect of a polymeric surfactant, Pluronic P-105 on the activity of electron transport chains in the mitochondria of HL-60 cells, the bioreduction rates of two membrane-localized lipophilic spin probes, 16-doxylstearic acid methyl ester (16-DSME) and 5-doxylstearic acid
Virginia Sara Grancieri Amaral et al.
Biochimica et biophysica acta. Biomembranes, 1861(4), 713-728 (2019-01-15)
Psd2 is a pea defensin with 47 amino acid residues that inhibits the growth of fungal species by an uncharacterized mechanism. In this work, Psd2 interactions with model membranes mimicking the lipid compositions of different organisms were evaluated. Protein-lipid overlay
P V Dubovskii et al.
Journal of molecular biology, 305(1), 137-149 (2000-12-15)
Carditoxins (CTXs) from cobra snake venoms, the basic 60-62 residue all-beta sheet polypeptides, are known to bind to and impair the function of cell membranes. To assess the membrane induced conformation and orientation of CTXs, the interaction of the P-type
K Tsuda et al.
Biochemical and biophysical research communications, 275(3), 946-954 (2000-09-07)
It has been shown that rheological abnormality might be an etiological factor in hypertension. Recent studies have revealed that human erythrocytes possess a nitric oxide (NO) synthase and that this activation might be involved in the regulation of rheological properties
O B Oleksiuk et al.
Biofizika, 48(2), 246-250 (2003-05-02)
The effect of lead acetate on the physical state of membrane lipids in human erythrocytes in vitro was studied using the lipophilic fluorescence probe 1,6-diphenyl-1,3,5-hexatriene and spin probes 16-doxyl-stearate and iminoxyl palmitic acid. It was shown that 2-10 microM lead
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