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Merck
CN

253421

Sigma-Aldrich

3-(2-碘乙酰氨基)-PROXYL

free radical

别名:

3-(2-碘乙酰氨基)-2,2,5,5-四甲基-1-吡咯烷基氧自由基

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About This Item

经验公式(希尔记法):
C10H18IN2O2
CAS号:
分子量:
325.17
MDL编号:
UNSPSC代码:
12352101
PubChem化学物质编号:
NACRES:
NA.22

表单

solid

mp

162-164 °C (lit.)

官能团

amide
iodo

储存温度

2-8°C

SMILES字符串

CC1(C)CC(NC(=O)CI)C(C)(C)N1[O]

InChI

1S/C10H18IN2O2/c1-9(2)5-7(12-8(14)6-11)10(3,4)13(9)15/h7H,5-6H2,1-4H3,(H,12,14)

InChI key

OQIGMSGDHDTSFA-UHFFFAOYSA-N

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一般描述

3-(2-Iodoacetamido)-PROXYL is a free radical used as a spin probe in spin labeling techniques. This technique is helpful in investigating the dynamic aspects of molecular interactions of substances, proteins, lipids, and cell membranes.

应用

巯基基团特异性自旋标记物。应用包括研究经臭氧处理的人和牛红细胞膜蛋白以及定位肌纤维中的肌球蛋白亚片段。含有硫代磷酸二酯的 DNA 片段可用自旋标记物进行标记。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

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Christoph Gmeiner et al.
Physical chemistry chemical physics : PCCP, 19(41), 28360-28380 (2017-10-17)
A combined method, employing NMR and EPR spectroscopies, has demonstrated its strength in solving structures of protein/RNA and other types of biomolecular complexes. This method works particularly well when the large biomolecular complex consists of a limited number of rigid
Na Li et al.
Scientific reports, 10(1), 393-393 (2020-01-17)
Fowlpox virus resolvase (Fpr) is an endonuclease that cleaves a broad range of branched DNA structures, including the Holliday junction (HJ), with little sequence-specificity. To better understand the mechanisms underlying its relaxed substrate specificity, we determined the crystal structures of
Site directed nitroxide spin labeling of oligonucleotides for NMR and EPR studies
Shepherd NE, et al.
Tetrahedron, 71(5), 813-819 (2015)
First spin-labeled cytisine derivatives
Polienko YF, et al.
Chemistry of Natural Compounds, 49(2), 311-315 (2013)
Anna I Nalepa et al.
Protein expression and purification, 88(1), 33-40 (2012-12-04)
α(1)-Microglobulin (α(1)m) is a protein of yet unresolved function occurring in blood plasma and urine. It consists of a lipocaline type of fold with two cysteine residues forming a disulfide bridge and the third cysteine-34 remaining a free, somewhat reactive

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