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Merck
CN

253367

Sigma-Aldrich

4-(2-碘乙酰氨基)-2,2,6,6-四甲基-1-哌啶氧自由基

free radical

别名:

4-(2-碘乙酰氨基)-2,2,6,6-四甲基-1-哌啶氧自由基, 4-(2-碘乙酰氨基)-2,2,6,6-四甲基哌啶-1-氧自由基

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About This Item

经验公式(希尔记法):
C11H20IN2O2
CAS号:
分子量:
339.19
MDL编号:
UNSPSC代码:
12352101
PubChem化学物质编号:
NACRES:
NA.22

表单

solid

mp

114-117 °C (lit.)

官能团

amide
iodo

储存温度

2-8°C

SMILES字符串

CC1(C)CC(CC(C)(C)N1[O])NC(=O)CI

InChI

1S/C11H20IN2O2/c1-10(2)5-8(13-9(15)7-12)6-11(3,4)14(10)16/h8H,5-7H2,1-4H3,(H,13,15)

InChI key

UCTVRHAKQRFPEZ-UHFFFAOYSA-N

应用

甲硫氨酸特异性自旋标记物。
用于研究磷酸烯醇式丙酮酸羧激酶和 GTP 结合位点的自旋标记物,还用于评估 SH1 和 SH2 肌球蛋白烷基化。

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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访问文档库

V P Timofeev et al.
Biophysics of structure and mechanism, 7(1), 41-49 (1980-01-01)
The rotational correlation time of two homologous cytoplasmic aspartate aminotransferase molecules isolated from pig and chicken hearts was obtained by spin-labeling technique. The maleimide and iodoacetamide spin-labels modifying external SH-groups of a protein were used. In the interpretation of ESR
E M Ostap et al.
Biochemistry, 32(26), 6712-6720 (1993-07-06)
We have used time-resolved electron paramagnetic resonance spectroscopy and caged ATP to detect nucleotide-induced changes in the conformational state of spin-labeled myosin heads (IASL-S1). Changes in the internal rotational dynamics of IASL-S1 were monitored with millisecond time resolution during the
G I Likhtenshtein et al.
Journal of biochemical and biophysical methods, 25(4), 219-229 (1992-12-01)
The theoretical considerations and experimental evidences discussed in this paper indicate that quantitative study of photochromic processes in labeled objects open up new possibilities for investigating microviscosity and conformation transitions in biological systems. The proposed method of photochrome labeling features
Biol. Membr., 1, 838-838 (1984)
C Coan et al.
Biochemistry, 21(13), 3214-3220 (1982-06-22)
The labeling kinetics of sarcoplasmic reticulum ATPase with the iodoacetamide spin probe N-(1-oxy-2,2,6,6-tetramethyl-4-piperidinyl)iodoacetamide were followed under conditions designed to selectively label all reactive groups. Approximately 1 mol of spin-label reacted per one 100 000-dalton ATPase chain, indicating only one residue

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