质量水平
检测方案
99%
形式
liquid
折射率
n20/D 1.419 (lit.)
bp
120-121 °C (lit.)
密度
0.824 g/mL at 25 °C (lit.)
SMILES字符串
C\C=C\C#N
InChI
1S/C4H5N/c1-2-3-4-5/h2-3H,1H3/b3-2+
InChI key
NKKMVIVFRUYPLQ-NSCUHMNNSA-N
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一般描述
研究了巴豆腈的神经毒性。研究了 1,4-二氮杂双环 [2，2] 辛烷（催化剂）存在下巴豆腈与苯甲醛的 Baylis-Hillman 反应机理。
警示用语：
Danger
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
closed cup
闪点(°C)
closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
Eduardo Balbuena et al.
Toxicology and applied pharmacology, 187(2), 89-100 (2003-03-22)
The neurotoxic compound crotononitrile has two isomeric forms, cis and trans. We compared the effects of these two isomers isolated by distillation from the commercially available mixture. Adult male Long-Evans rats were administered vehicle control, cis-crotononitrile (80, 100, and 120
Carla Soler-Martín et al.
Toxicological sciences : an official journal of the Society of Toxicology, 96(1), 123-132 (2006-12-13)
Several nitriles have been demonstrated to cause hair cell loss in the inner ear of the rat, but the susceptibility of other species to this toxic effect has not been investigated. Adult male Swiss mice were administered (po) control vehicle
J Llorens et al.
Toxicology and applied pharmacology, 123(2), 199-210 (1993-12-01)
Animals exposed to 3,3'-iminodipropionitrile (IDPN) or to several similar nitriles develop a permanent syndrome of behavioral abnormalities. The present work addressed the hypothesis that this syndrome is caused by a toxic effect of these nitriles on the peripheral vestibular system.
H Tanii et al.
Nihon eiseigaku zasshi. Japanese journal of hygiene, 54(2), 459-466 (1999-09-10)
Nitriles are widely used in industry as plastics, solvents, and synthetic intermediates. It has been shown that the thermal degradation of acrylonitrile-based plastics leads to the emission of a great variety of nitriles. Exposure of humans and experimental animals to
H Tanii et al.
Toxicology letters, 58(3), 323-328 (1991-11-01)
The effects of allylnitrile (ALN), which induces a long-term dyskinesia in mice, on the metabolism of serotonin (5-HT) and dopamine (DA) were studied after a single administration. One day after injection, ALN produced a significant increase in the levels of
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