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检测方案
98%
形式
solid
bp
101 °C/5 mmHg (lit.)
mp
42-44 °C (lit.)
SMILES字符串
Clc1cccc(Cl)c1N=C=O
InChI
1S/C7H3Cl2NO/c8-5-2-1-3-6(9)7(5)10-4-11/h1-3H
InChI key
HMVKMAMIRAVXAN-UHFFFAOYSA-N
应用
2,6-Dichlorophenyl isocyanate has been used in the preparation of pyridine-urea analog.
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Luping Liu et al.
Bioorganic & medicinal chemistry letters, 13(22), 3979-3982 (2003-11-01)
Development for a class of potent 3,4-dihydropyrido(3,2-d)pyrimidone inhibitors of p38a MAP kinase is described. Modification of N-1 aryl and C-6 arylsulfide in 3,4-dihydropyrido(3,2-d)pyrimidone analogues for the interaction with the hydrophobic pockets in p38 active site is also discussed.
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