24940
4-氯-3-甲基苯酚
≥98.0% (HPLC)
别名:
4-氯间甲酚, PCMC
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线性分子式:
ClC6H3(CH3)OH
化学文摘社编号:
分子量:
142.58
Beilstein:
1237629
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
质量水平
方案
≥98.0% (HPLC)
表单
pellets
沸点
235 °C (lit.)
mp
63-65 °C (lit.)
溶解性
methanol: soluble 1 g/10 mL, clear, colorless
water: soluble
SMILES字符串
Cc1cc(O)ccc1Cl
InChI
1S/C7H7ClO/c1-5-4-6(9)2-3-7(5)8/h2-4,9H,1H3
InChI key
CFKMVGJGLGKFKI-UHFFFAOYSA-N
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一般描述
4-Chloro-3-methylphenol is an organic compound belonging to the class of monochlorinated m-cresol. It is used as an organic building block in chemical synthesis.
应用
4-Chloro-3-methylphenol has been used in paint formulations.
警示用语：
Danger
危险分类
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1C - Skin Sens. 1B - STOT SE 3
靶器官
Respiratory system
储存分类代码
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 2
闪点(°F)
244.4 °F - closed cup
闪点(°C)
118.0 °C - closed cup
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
危险化学品
此项目有
Quantitative measurement of Ca²(+) in the sarcoplasmic reticulum lumen of mammalian skeletal muscle.
Andrew P Ziman et al.
Biophysical journal, 99(8), 2705-2714 (2010-10-21)
Skeletal muscle stores Ca²(+) in the sarcoplasmic reticulum (SR) and releases it to initiate contraction, but the concentration of luminal Ca²(+) in the SR ([Ca²(+)](SR)) and the amount that is released by physiological or pharmacological stimulation has been difficult to
Ramón Jiménez-Moreno et al.
Pflugers Archiv : European journal of physiology, 459(5), 725-735 (2010-01-14)
The endoplasmic/sarcoplasmic reticulum (ER/SR) plays a crucial role in cytoplasmic signalling in a variety of cells. It is particularly relevant to skeletal muscle fibres, where this organelle constitutes the main Ca2+ store for essential functions, such as contraction. In this
Roel Mallants et al.
The Journal of pharmacy and pharmacology, 61(7), 883-890 (2009-07-11)
The aim was to establish a preclinical in-vitro system of the nasal mucosa for the simultaneous evaluation of nasal absorption and effects on ciliary activity. Human nasal epithelial cells were grown in collagen-coated transport inserts with transparent polyethylene terephthalate membranes
A Peñalver et al.
Journal of chromatography. A, 839(1-2), 253-260 (1999-05-18)
Three pesticides usually added to paint formulations, Irgarol 1051, dichlofluanid and 4-chloro-3-methylphenol, were determined by solid-phase microextraction (SPME) with 85-micron polyacrylate fibers and gas chromatography-mass spectrometry. The parameters affecting the SPME process (the pH, the addition of salt to the
Benjamin L Prosser et al.
American journal of physiology. Cell physiology, 299(5), C891-C902 (2010-08-06)
The role of S100A1 in skeletal muscle is just beginning to be elucidated. We have previously shown that skeletal muscle fibers from S100A1 knockout (KO) mice exhibit decreased action potential (AP)-evoked Ca(2+) transients, and that S100A1 binds competitively with calmodulin
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