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7-氨基-4-（三氟甲氧基）香豆素
≥99%
别名:
香豆素 151
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关于此项目
经验公式（希尔记法）:
C10H6F3NO2
化学文摘社编号:
分子量:
229.16
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
258-599-1
Beilstein/REAXYS Number:
4456797
MDL number:
产品名称
7-氨基-4-（三氟甲氧基）香豆素, ≥99%
InChI key
JBNOVHJXQSHGRL-UHFFFAOYSA-N
InChI
1S/C10H6F3NO2/c11-10(12,13)7-4-9(15)16-8-3-5(14)1-2-6(7)8/h1-4H,14H2
SMILES string
Nc1ccc2c(OC(=O)C=C2C(F)(F)F)c1
assay
≥99%
form
(Powder or Crystals or Chunks)
technique(s)
titration: suitable
mp
221-222 °C (lit.)
λmax
≤207 nm
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Quality Level
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Application
适于用作激光染料
General description
7-氨基-4-（三氟甲基）香豆素（AFC）是用于检测蛋白酶的一种新型荧光标记物。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
S W Cox et al.
Journal of periodontal research, 25(3), 164-171 (1990-05-01)
Substrate impregnated paper discs were prepared using peptidyl derivatives of 7-amino-4-trifluoromethylcoumarin (AFC). After incubation with test solutions, the green, UV-induced fluorescence of AFC liberated by enzyme activity was distinguishable from the blue-violet fluorescence of the substrates. The AFC could then
Synthesis and chemistry of 7-amino-4-(trifluoromethyl)coumarin and its amino acid and peptide derivatives
Bissell E R
The Journal of Organic Chemistry, 45, 2283?2287-2283?2287 (1980)
E D Pederson et al.
Journal of clinical periodontology, 21(8), 519-525 (1994-09-01)
Treponema denticola (Td) and Porphyromonas gingivalis (Pg) are associated with human moderate and severe adult periodontal diseases. This study quantifies these two anaerobes and their trypsin-like (TL) activities in subgingival plaque collected from both clinically healthy and periodontally diseased sites
Franziska Ebert et al.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 61, 126563-126563 (2020-06-13)
Arsenolipids, especially arsenic-containing hydrocarbons (AsHC), are an emerging class of seafood originating contaminants. Here we toxicologically characterize a recently identified oxo-AsHC 332 metabolite, thioxo-AsHC 348 in cultured human liver (HepG2) cells. Compared to results of previous studies of the parent
S W Cox et al.
Archives of oral biology, 32(9), 599-605 (1987-01-01)
The cysteine proteinases cathepsins B and L have collagenolytic potential and so have been implicated in connective-tissue breakdown in chronic periodontitis. Synthetic peptide substrates are often used to detect proteolytic enzymes. The action of homogenates of inflamed gingiva tissue against
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