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质量水平
方案
97%
表单
powder
mp
117-119 °C (lit.)
SMILES字符串
[Br-].CCCCCCCCCCCC[N+](C)(C)CCOc1ccccc1
InChI
1S/C22H40NO.BrH/c1-4-5-6-7-8-9-10-11-12-16-19-23(2,3)20-21-24-22-17-14-13-15-18-22;/h13-15,17-18H,4-12,16,19-21H2,1-3H3;1H/q+1;/p-1
InChI key
OJIYIVCMRYCWSE-UHFFFAOYSA-M
一般描述
度米芬(DMP)是一种季铵盐化合物，属于苯酚醚类物质。可用作阳离子表面活性剂。
应用
- 多菲芬在抗菌方面的应用：一项临床试验评估了含多芬溴化剂和其他季铵化合物的漱口水的有效性，显示其能够显著减少牙龈炎，支持其在牙科保健产品中的使用（Rosa and Sturzenberger, 1976）。
- 多菲芬溴化剂的毒性和安全性研究：最近的一项研究探索了多菲芬在体外和体内模型中诱导的促心律失常效应，为其在制药应用中的应用提供了至关重要的安全性信息（Long et al., 2021）。
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
F Scaglione et al.
International journal of clinical pharmacology research, 3(5), 357-361 (1983-01-01)
Thirty-one patients (21 M and 10 F), affected by acute infectious dental disease, were treated with domifen bromide (A) or placebo (Pl). It was found that A had a beneficial effect on the results of clinical controls and reduced the
F Scaglione et al.
International journal of clinical pharmacology research, 3(4), 261-264 (1983-01-01)
By means of a double blind, placebo controlled trial, we have studied 29 patients (14 M and 15 F) affected by different acute infectious oral diseases. Our results suggest that domifen bromide may be useful in treating infectious oral diseases
[Antiseptic activity of domiphen bromide on the yeast Candida in the mouth].
P Goumas et al.
Stomatologia, 41(5), 249-257 (1984-09-01)
Julien R G Navarro et al.
Nanotechnology, 23(46), 465602-465602 (2012-10-26)
A great number of works have focused their research on the synthesis, design and optical properties of gold nanoparticles for potential biological applications (bioimaging, biosensing). For this kind of application, sharp gold nanostructures appear to exhibit the more interesting features
Thermophysical Studies on Molecular Interactions of Semicarbazide Hydrochloride/Domiphen Bromide in Aqueous Deep Eutectic Solvent Media at Various Temperatures
Majid Q, et al.
Journal of Chemical and Engineering Data, 67(10), 2974-2985 (2022)
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