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质量水平
方案
98%
表单
solid
mp
155-157 °C (lit.)
SMILES字符串
Nc1ccccc1S(N)(=O)=O
InChI
1S/C6H8N2O2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
InChI key
YAZSBRQTAHVVGE-UHFFFAOYSA-N
基因信息
human ... CA1(759) , CA2(760) , CA5A(763) , CA5B(11238) , CA9(768)
mouse ... Car13(71934)
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
PloS one, 5(10) (2010-10-20)
Classical antiviral therapies target viral proteins and are consequently subject to resistance. To counteract this limitation, alternative strategies have been developed that target cellular factors. We hypothesized that such an approach could also be useful to identify broad-spectrum antivirals. The
Farmaco (Societa chimica italiana : 1989), 52(6-7), 375-378 (1997-06-01)
The synthesis of pyrrolo[2,1-d][1,2,5]benzothiadiazepin-7(6H)-one 5,5-dioxide has been achieved by reaction between 2-(1H-pyrrol-1-yl)benzenesulfonamide and triphosgene. N-Ethylation of the tricyclic derivative afforded 6-ethylpyrrolo[2,1-d][1,2,5] benzothiadiazepin-7(6H)-one 5,5-dioxide, also obtained by the action of trifosgene on N-ethyl 2-(1H-pyrrol-1-yl)benzenesulfonamide. Preparation of pyrrole derivatives from 2-aminobenzenesulfonamide and
Bioorganic & medicinal chemistry, 16(6), 2955-2967 (2008-01-16)
Inhibition of the hepatitis C virus (HCV) NS3 protease has emerged as an attractive approach to defeat the global hepatitis C epidemic. In this work, we present the synthesis and biochemical evaluation of HCV NS3 protease inhibitors comprising a non-natural
Nitrogen-15 nuclear magnetic resonance study of benzenesulfonamide and cyanate binding to carbonic anhydrase.
Biochemistry, 22(11), 2658-2664 (1983-05-24)
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