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About This Item
经验公式（希尔记法）:
C8H15NO
CAS号:
分子量:
141.21
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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方案
95%
表单
solid
沸点
73 °C/1 mmHg (lit.)
mp
58-61 °C (lit.)
储存温度
−20°C
SMILES字符串
CC1(C)CC(C)(C)[N+]([O-])=C1
InChI
1S/C8H15NO/c1-7(2)5-8(3,4)9(10)6-7/h6H,5H2,1-4H3
InChI key
GUQARRULARNYQZ-UHFFFAOYSA-N
一般描述
The ESR spectrum of 3,3,5,5-tetramethyl-1-pyrroline N-oxide was studied.
应用
3,3,5,5-Tetramethyl-1-pyrroline N-oxide was used as a spin traping reagent.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
G R Buettner et al.
Free radical biology & medicine, 8(1), 57-60 (1990-01-01)
The spin trap 3,3,5,5-tetramethylpyrroline-N-oxide (M4PO) reacts with superoxide to produce a short-lived spin adduct (M4PO/.OOH, AN = 14.0 G, AH = 6.5 G) that decays by a first-order process (t1/2 approximately 35 s at pH 7.4). This short lifetime may
Spin trapping chemistry of 3, 3, 5, 5-tetramethylpyrroline-N-oxide: an improved cyclic spin trap.
Janzen EG, et al.
Canadian Journal of Chemistry, 59(4), 756-758 (1981)
H Mori et al.
Biochemistry and molecular biology international, 32(3), 523-529 (1994-03-01)
To determine whether hydroxyl radicals (.OH) are generated in the hypoxanthine (HPX)-xanthine oxidase (XOD) reaction, we examined the electron paramagnetic resonance (EPR) spectra of the spin adducts formed. In the EPR study, we used 3,3,5,5-tetramethyl-1-pyrroline-N-oxide (M4PO) as a spin trap
G M Rosen et al.
Journal of medicinal chemistry, 31(2), 428-432 (1988-02-01)
Two nitrones, 3,3-diethyl-5,5-dimethylpyrroline 1-oxide (DEDMPO) and 3,3,5,5-tetramethylpyrroline 1-oxide (M4PO), were synthesized by the zinc/ammonium chloride reduction of appropiately substituted gamma-nitrocarbonyl compounds, followed by addition of methylmagnesium bromide to the resulting intermediate nitrones. The lipophilicities of these nitrones were estimated by
S Unchern et al.
Neurochemical research, 23(1), 97-102 (1998-03-03)
We compared neurotoxicity of piperine and low K+ on cultured cerebellar granule neurons. As considered from lactate dehydrogenase release and 3-(4,5-dimethylthiazol-2-yl)-2,5 diphenyl tetrazolium bromide reduction, both piperine and shifting from high K+ (25 mM) to low K+ (5.4 mM) were
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