244007
3,3,5,5-四甲基-1-吡咯啉-N-氧化物
95%
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关于此项目
经验公式（希尔记法）:
C8H15NO
化学文摘社编号:
分子量:
141.21
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
95%
Form:
solid
InChI
1S/C8H15NO/c1-7(2)5-8(3,4)9(10)6-7/h6H,5H2,1-4H3
SMILES string
CC1(C)CC(C)(C)[N+]([O-])=C1
InChI key
GUQARRULARNYQZ-UHFFFAOYSA-N
assay
95%
form
solid
bp
73 °C/1 mmHg (lit.)
mp
58-61 °C (lit.)
storage temp.
−20°C
General description
The ESR spectrum of 3,3,5,5-tetramethyl-1-pyrroline N-oxide was studied.
Application
3,3,5,5-Tetramethyl-1-pyrroline N-oxide was used as a spin traping reagent.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Vesselina Gadjeva et al.
Toxicology letters, 144(3), 289-294 (2003-08-21)
We have studied the toxic effect of the alkylating antitumor drug N'-cyclohexyl-N-(2-chloroethyl)-N-nitrosourea (lomustine, CCNU) on Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) strains, alone and in presence of oxygen radical-scavenging substances [Vitamin E, stable nitroxyl radical 2,2,6,6-tetramethylpiperidine-N-oxyl (TMPO)
M Nishi et al.
Biochemistry international, 27(4), 651-659 (1992-08-01)
2,5,5-Trimethyl-1-pyrroline-N-oxide (M3PO) and 3,3,5,5-tetramethyl-1-pyrroline-N-oxide (M4PO) were examined for their potential as spin traps used in biological samples, and the results obtained for M3PO and M4PO were compared with those of 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) reported previously. The rate constants for the reactions
S Pietri et al.
European journal of biochemistry, 186(1-2), 163-173 (1989-12-08)
Real-time monitoring of spin-trapped oxygen-derived free radicals released by the isolated ischemic and reperfused rat heart has been achieved by ESR analysis of the coronary effluents using continuous flow detection and high-speed acquisition techniques. Two nitrone spin traps 5,5-dimethyl pyrroline
W D Yang et al.
Free radical research communications, 18(2), 99-106 (1993-01-01)
When aqueous solutions of the spin trap 5,5'-dimethyl-1-pyrroline-N-oxide (DMPO) are treated with hydrogen peroxide in the presence of either FeII or light, the hydroxyl radical adduct DMPO-OH is formed, with a characteristic 4 line ESR spectrum. When oxy- or metmyoglobin
M Culcasi et al.
Biochemical and biophysical research communications, 164(3), 1274-1280 (1989-11-15)
A new approach for in vivo spin trapping and quantitation of oxygen-derived free radicals has been developed using a continuous flow high speed ESR detection system. Spin adducts of OH. were detected as 1:1:1:1:1:1 sextets (aN=15.2 G, aH=16.8 G, g=2.0055)
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