242632
2-氯乙基甲基硫醚
97%
别名:
2-(甲硫基)氯乙烷, Hemisulfur mustard
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关于此项目
线性分子式:
ClCH2CH2SCH3
化学文摘社编号:
分子量:
110.61
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-828-6
Beilstein/REAXYS Number:
1731033
MDL number:
产品名称
2-氯乙基甲基硫醚, 97%
InChI key
MYFKLQFBFSHBPA-UHFFFAOYSA-N
InChI
1S/C3H7ClS/c1-5-3-2-4/h2-3H2,1H3
SMILES string
CSCCCl
assay
97%
form
liquid
refractive index
n20/D 1.496 (lit.)
bp
55-56 °C/30 mmHg (lit.)
density
1.11 g/mL at 25 °C (lit.)
functional group
chloro
thioether
storage temp.
2-8°C
Quality Level
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Application
2-Chloroethyl methyl sulfide is a monofunctional chemical analog of sulfur mustard and has been used to study the potential of 2,6-dithiopurine as an antagonist of sulfur mustard.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Carc. 1A - Flam. Liq. 3 - Skin Corr. 1B
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
107.6 °F - closed cup
flash_point_c
42 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
J R King et al.
Toxicology and applied pharmacology, 104(1), 167-179 (1990-06-01)
Previous research has shown the isolated perfused porcine skin flap (IPPSF) to be a novel in vitro experimental model for investigating xenobiotic percutaneous absorption. In this study, the IPPSF was used to biochemically and morphologically assess the dermatotoxicity of 2-chloroethyl
G R Klinefelter et al.
Journal of andrology, 18(2), 139-150 (1997-03-01)
In a previous study, we found that ethane dimethanesulphonate (EDS) compromised the fertilizing ability of proximal cauda epididymal sperm from the rat within 4 days of exposure, an effect that persisted in castrated, testosterone (T)-implanted animals, establishing direct action on
Bruna Scaggiante et al.
Hematological oncology, 31(2), 110-116 (2012-08-30)
The elongation factor 1A proteins (eEF1A1/A2) are known to play a role in tumours. We previously found that a more basic isoform of eEF1A (MBI-eEF1A) is present in the cytoskeletal/nuclear-enriched extracts of CCRF-CEM T-lymphoblasts but not in those of normal
Y W Sohn et al.
Carcinogenesis, 17(6), 1361-1364 (1996-06-01)
Vinthionine (S-vinyl-DL-homocysteine) is hepatocarcinogenic in rats and mice. [Vinyl-14C]vinthionine binds covalently to rat liver DNA, RNA and protein in vivo, but not in vitro. This amino acid is directly mutagenic in Salmonella typhimurium TA100 and TA1535; the mechanism of its
K Leslie Powell et al.
Chemical research in toxicology, 23(3), 497-503 (2010-01-07)
Sulfur mustard (bis-(2-chloroethyl)sulfide) is a well-known chemical warfare agent that induces debilitating cutaneous toxicity in exposed individuals. It is also known to be carcinogenic and mutagenic because of its ability to damage DNA via electrophilic attack. We previously showed that
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