蒸汽密度
~6.5 (vs air)
质量水平
蒸汽压
11.7 mmHg ( 25 °C)
检测方案
≥99%
形式
liquid
折射率
n20/D 1.539 (lit.)
bp
131-132 °C (lit.)
mp
8-11 °C (lit.)
溶解性
water: soluble 250 part
alcohol: miscible(lit.)
diethyl ether: miscible(lit.)
密度
2.18 g/mL at 25 °C (lit.)
SMILES字符串
BrCCBr
InChI
1S/C2H4Br2/c3-1-2-4/h1-2H2
InChI key
PAAZPARNPHGIKF-UHFFFAOYSA-N
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一般描述
1,2-Dibromoethane (DBE) is an organobromine compound that is used as an ‘entrainment reagent′ to activate magnesium in Grignard reagents. It is also a useful reagent for activating zinc. DBE is used as an intermediate in the synthesis of dyes, pesticides and pharmaceuticals.
应用
1,2-Dibromoethane can be used as a reagent to prepare:
It can also be used as a bromine source in organic synthesis to brominate carbanions.
- Vinyl bromide and 1,2-disubstituted ethane derivatives.
- Vinyl aromatic compounds by palladium-catalyzed cross-coupling reaction with various arylboronic acids via in situ formation of vinyl bromide.
- 2-arylsulfonyl hydrazones by reacting with aryldiazonium tetrafluoroborates, sulfur dioxide and hydrazines.
It can also be used as a bromine source in organic synthesis to brominate carbanions.
其他说明
储存时颜色可能变深
警示用语:
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
新产品
1, 2-dibromoethane-A versatile reagent in organic synthesis
Synlett, 2008(10), 1579-1580 (2008)
1, 2-Dibromoethane
Encyclopedia of Reagents for Organic Synthesis, Second Edition (2001)
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Saturation vapor pressures and transition enthalpies of low-volatility organic molecules of atmospheric relevance: from dicarboxylic acids to complex mixtures.
Chemical reviews, 115(10), 4115-4156 (2015-05-02)
A four-component reaction of aryldiazonium tetrafluoroborates, sulfur dioxide, 1,2-dibromoethane, and hydrazines
Organic & Biomolecular Chemistry, 13(41), 10370-10375 (2015)
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